The risks of long-term use of proton pump inhibitors: a critical review

M Jaynes, AB Kumar - Therapeutic advances in drug safety, 2019 - journals.sagepub.com
Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

Prophylaxis against upper gastrointestinal bleeding in hospitalized patients

D Cook, G Guyatt - New England Journal of Medicine, 2018 - Mass Medical Soc
Preventing Gastrointestinal Bleeding in the Hospital Acid suppression is widely used to
lower the risk of gastrointestinal bleeding in critically ill patients, and the practice has spread …

Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive …

PJ Young, SM Bagshaw, AB Forbes, AD Nichol… - Jama, 2020 - jamanetwork.com
Importance Proton pump inhibitors (PPIs) or histamine-2 receptor blockers (H 2 RBs) are
often prescribed for patients as stress ulcer prophylaxis drugs in the intensive care unit …

Variations in the use of perioperative multimodal analgesic therapy

KS Ladha, E Patorno, KF Huybrechts, J Liu… - …, 2016 - pubs.asahq.org
Background Practice guidelines for perioperative pain management recommend that
multimodal analgesic therapy should be used for all postsurgical patients. However, the …

Early β-blocker use and in-hospital mortality in patients with Takotsubo cardiomyopathy

T Isogai, H Matsui, H Tanaka, K Fushimi, H Yasunaga - Heart, 2016 - heart.bmj.com
Objective A catecholamine-mediated mechanism has been implicated in the pathogenesis
of Takotsubo cardiomyopathy (TC). However, the impact of β-blockers in acute-phase …

Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study

E Patorno, MD Neuman, S Schneeweiss, H Mogun… - Bmj, 2014 - bmj.com
Objective To evaluate the effect of anesthesia type on the risk of in-hospital mortality among
adults undergoing hip fracture surgery in the United States. Design Retrospective cohort …

Stress ulcer prophylaxis

JF Barletta, JJ Bruno, MS Buckley… - Critical care medicine, 2016 - journals.lww.com
Objectives: Stress ulcer prophylaxis is commonly administered to critically ill patients for the
prevention of clinically important stress-related mucosal bleeding from the upper …

Proton pump inhibitor use represents an independent risk factor for myocardial infarction

CJ Shih, YT Chen, SM Ou, SY Li, TJ Chen… - International journal of …, 2014 - Elsevier
Background There is substantial debate regarding the development of acute coronary
syndrome in patients using proton pump inhibitors (PPIs) combined with clopidogrel …

Effect of early rehabilitation by physical therapists on in-hospital mortality after aspiration pneumonia in the elderly

R Momosaki, H Yasunaga, H Matsui… - Archives of physical …, 2015 - Elsevier
Objective To clarify the effect of early rehabilitation by physical therapists on in-hospital
mortality among elderly patients with aspiration pneumonia. Design A retrospective cohort …

Proton pump inhibitor on susceptibility to COVID-19 and its severity: a systematic review and meta-analysis

R Pranata, I Huang, S Lawrensia, J Henrina… - Pharmacological …, 2021 - Springer
Background The negative impacts of proton pump inhibitor (PPI), including the risk of
pneumonia and mortality, have been reported previously. This meta-analysis aimed to …