Diagnosis and treatment of acute myocarditis: a review
E Ammirati, JJ Moslehi - Jama, 2023 - jamanetwork.com
Importance Acute myocarditis, defined as a sudden inflammatory injury to the myocardium,
affects approximately 4 to 14 people per 100 000 each year globally and is associated with …
affects approximately 4 to 14 people per 100 000 each year globally and is associated with …
Dilated cardiomyopathy: causes, mechanisms, and current and future treatment approaches
Dilated cardiomyopathy is conventionally defined as the presence of left ventricular or
biventricular dilatation or systolic dysfunction in the absence of abnormal loading conditions …
biventricular dilatation or systolic dysfunction in the absence of abnormal loading conditions …
2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …
AR Lyon, T Lopez-Fernandez, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …
that, unless otherwise provided for by national regulations, offlabel use of medication should …
Abatacept/ruxolitinib and screening for concomitant respiratory muscle failure to mitigate fatality of immune-checkpoint inhibitor myocarditis
JE Salem, M Bretagne, B Abbar, S Leonard-Louis… - Cancer Discovery, 2023 - AACR
Abstract Immune-checkpoint-inhibitor (ICI)–associated myotoxicity involves the heart
(myocarditis) and skeletal muscles (myositis), which frequently occur concurrently and are …
(myocarditis) and skeletal muscles (myositis), which frequently occur concurrently and are …
Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer
Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …
the world. The emerging field of cardio-oncology has revealed that these seemingly …
Sex-specific cardiovascular risks of cancer and its therapies
In both cardiovascular disease and cancer, there are established sex-based differences in
prevalence and outcomes. Males and females may also differ in terms of risk of cardiotoxicity …
prevalence and outcomes. Males and females may also differ in terms of risk of cardiotoxicity …
Cardiomuscular biomarkers in the diagnosis and prognostication of immune checkpoint inhibitor myocarditis
LH Lehmann, MB Heckmann, G Bailly, D Finke… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Immune checkpoint inhibitors (ICIs) are approved for multiple cancers but
can result in ICI-associated myocarditis, an infrequent but life-threatening condition …
can result in ICI-associated myocarditis, an infrequent but life-threatening condition …
Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
Immune checkpoint inhibitors (ICIs) are an effective therapy for various cancers; however,
they can induce immune-related adverse events (irAEs) as a side effect. Myocarditis is an …
they can induce immune-related adverse events (irAEs) as a side effect. Myocarditis is an …
Immune-checkpoint inhibitor-mediated myocarditis: CTLA4, PD1 and LAG3 in the heart
Immune-checkpoint inhibitors (ICIs) have revolutionized oncology, with nearly 50% of all
patients with cancer eligible for treatment with ICIs. However, patients on ICI therapy are at …
patients with cancer eligible for treatment with ICIs. However, patients on ICI therapy are at …
Hormonal therapies up-regulate MANF and overcome female susceptibility to immune checkpoint inhibitor myocarditis
Immune checkpoint inhibitors (ICIs) have been increasingly used in combination for cancer
treatment but are associated with myocarditis. Here, we report that tumor-bearing mice …
treatment but are associated with myocarditis. Here, we report that tumor-bearing mice …