Esomeprazole magnesium (ESM), a salt of esomeprazole (ESO), has low oral bioavailability
owing to its poor solubility. This study aimed to improve the solubility and bioavailability of …

Some drugs have low bioavailability due to their poor aqueous solubility and/or slow
dissolution rate in biological fluids. Stiripentol (STP) is a novel anticonvulsant drug that is …

Ternary solid solutions composed of nifedipine (NDP), amino methacrylate copolymer
(AMCP), and polysorbate (PS) 20, 60, or 65 were prepared using a solvent evaporation …

Solid dispersion is an attractive tool of pharmaceutical technology used to improve the
physical properties of drugs, among these properties is the solubility of the drugs …

Current study was designed with an aim to improve the solubility and dissolution profile of
artesunate by preparing solid dispersions through solvent evaporation and freeze-drying …

Pitavastatin (PTV) is a potent lipid lowering drug that acts on hepatocytes by blocking the 3-
hydroxy-3-methylglutaryl-CoA reductase enzyme. As a Biopharmaceutical Classification …

Objective: Investigation of in vitro/in vivo behaviour of fast-dissolving tablets containing solid
dispersions of oxcarbazepine is the focus of the present research work. Methods: The effect …

This study was mainly designed to solve the drawbacks of conventional verapamil solid
dosage form, low bioavailability and limited clinical efficacy, by preparing solid dispersion …

Практична значимість. Проведені дослідження доводять, що до перспективних методів
утворення твердих дисперсних систем, що дозволяють забезпечити значне …

In the present study, a model drug, with its low permeable and low aqueous soluble
properties, was selected to produce microparticles using an anti-solvent precipitation …