Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: a systematic review for the EAACI guidelines

I Agache, Y Song, P Alonso‐Coello, Y Vogel, C Rocha… - Allergy, 2021 - Wiley Online Library
This systematic review evaluates the efficacy and safety of biologicals for chronic
rhinosinusitis with nasal polyps (CRSwNP) compared with the standard of care. PubMed …

Updates in biologic therapy for chronic rhinosinusitis with nasal polyps and NSAID‐exacerbated respiratory disease

X Xu, S Reitsma, DY Wang, WJ Fokkens - Allergy, 2022 - Wiley Online Library
Chronic rhinosinusitis with nasal polyps (CRSwNP) associated with type 2 inflammation and
non‐steroidal anti‐inflammatory drug (NSAID)‐exacerbated respiratory disease (N‐ERD) …

Endoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial

ES Lourijsen, S Reitsma, M Vleming… - The Lancet …, 2022 - thelancet.com
Background Endoscopic sinus surgery (ESS) is a common operation for patients with
chronic rhinosinusitis with nasal polyps (CRSwNP) when medical therapy alone is …

Comparison of different biologics for treating chronic rhinosinusitis with nasal polyps: a network analysis

S Cai, S Xu, H Lou, L Zhang - The Journal of Allergy and Clinical …, 2022 - Elsevier
Background Several promising clinical trials have demonstrated the effects of type 2
biologics compared with placebos in chronic rhinosinusitis with nasal polyps (CRSwNP) …

A comparative analysis of endoscopic sinus surgery versus biologics for treatment of chronic rhinosinusitis with nasal polyposis

A Miglani, ZM Soler, TL Smith, JC Mace… - International forum of …, 2023 - Wiley Online Library
Background Comparative effectiveness research between endoscopic sinus surgery (ESS)
and biologic therapy for severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is a …

The role of biologics in chronic rhinosinusitis with nasal polyps

GB Patel, AT Peters - Ear, Nose & Throat Journal, 2021 - journals.sagepub.com
Biologic therapy is a new treatment option for patients with chronic rhinosinusitis with nasal
polyps (CRSwNP). Currently, the only biologic with Food and Drug Administration–approval …

Current insight into treatment of chronic rhinosinusitis: phenotypes, endotypes, and implications for targeted therapeutics

N Chapurin, J Wu, AB Labby, RK Chandra… - Journal of Allergy and …, 2022 - Elsevier
Chronic rhinosinusitis is characterized by persistent locoregional mucosal inflammation of
the paranasal sinuses and upper airway that has substantial associated health care costs …

Cost‐effectiveness analysis comparing dupilumab and aspirin desensitization therapy for chronic rhinosinusitis with nasal polyposis in aspirin‐exacerbated …

M Yong, YQ Wu, J Howlett, J Ballreich… - … Forum of Allergy & …, 2021 - Wiley Online Library
Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) in the setting of aspirin‐
exacerbated respiratory disease (AERD) is a disease that is difficult to treat and prone to …

Management of chronic rhinosinusitis with nasal polyposis in the era of biologics

JC Morse, C Miller, B Senior - Journal of Asthma and Allergy, 2021 - Taylor & Francis
Purpose of Review Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a phenotypic
designation of the broader condition of chronic rhinosinusitis. The advent of targeted …

Multidisciplinary consensus on a stepwise treatment algorithm for management of chronic rhinosinusitis with nasal polyps.

JK Han, JV Bosso, SH Cho… - … forum of allergy & …, 2021 - search.ebscohost.com
Keywords: chronic rhinosinusitis; corticosteroid implant; endoscopic sinus surgery; nasal
polyps; T2 biologic; topical corticosteroid; treatment algorithm EN chronic rhinosinusitis …