Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease
that have shown promise in laboratory models of disease and early clinical trials. In contrast …

Dendritic cells (DCs) are a complex network of specialised antigen-presenting cells that are
critical initiators of adaptive immunity. Targeting antigen directly to DCs in situ is a …

Extracellular vesicles (EVs) are promising carriers for the delivery of a variety of chemical
and biological drugs. However, their efficacy is limited by the lack of cellular specificity …

T cells are often referred to as the 'guided missiles' of our immune system because of their
capacity to traffic to and accumulate at sites of infection or disease, destroy infected or …

Priming of CD8+ T cells by dendritic cells (DCs) is crucial for the generation of effective
antitumor immune responses. Here, we describe a liposomal vaccine carrier that delivers …

Snakes, scorpions, and spiders are venomous animals that pose a threat to human health,
and severe envenomings from the bites or stings of these animals must be treated with …

Background: Cellular rejection after heart transplantation imparts significant morbidity and
mortality. Current immunosuppressive strategies are imperfect, target recipient T cells, and …

The human skin is an attractive anti-tumor vaccination site due to the vast network of
dendritic cell (DC) subsets that carry antigens to the draining lymph nodes and stimulate …

IFNγ is traditionally known as a proinflammatory cytokine with diverse roles in antimicrobial
and antitumor immunity. Yet, findings regarding its sources and functions during the …

Cancer vaccine development is inhibited by a lack of strategies for directing dendritic cell
(DC) induction of effective tumor-specific cellular immunity. Pathogen engagement of DC …