Towards interpretable imaging genomics analysis: methodological developments and applications
X Cen, W Dong, W Lv, Y Zhao, F Dubee, AFA Mentis… - Information …, 2024 - Elsevier
Identifying the relationship between imaging features and genetic variation (a term coined
“imaging genomics”) offers valuable insight into the pathogenesis of cancer, as well as …
“imaging genomics”) offers valuable insight into the pathogenesis of cancer, as well as …
Age-associated cortical similarity networks correlate with cell type-specific transcriptional signatures
J Niu, Q Jiao, D Cui, R Dou, Y Guo, G Yu… - Cerebral …, 2024 - academic.oup.com
Human brain structure shows heterogeneous patterns of change across adults aging and is
associated with cognition. However, the relationship between cortical structural changes …
associated with cognition. However, the relationship between cortical structural changes …
Multi-omics data integration reveals novel genes related to autoimmune hypothyroidism in the brain: A molecular basis for the brain–thyroid axis
H Yu, Z Li, X Gao, X Liu, W Cui, N Li, X Lian, C Li… - Progress in Neuro …, 2024 - Elsevier
Background The mechanisms underlying the complex relationship between autoimmune
hypothyroidism and neurological disorders remain unclear. We conducted a comprehensive …
hypothyroidism and neurological disorders remain unclear. We conducted a comprehensive …
Deciphering causal relationships between cell type-specific genetic factors and brain imaging-derived phenotypes and disorders
The integration of expression quantitative trait loci (eQTLs) and genome-wide association
study (GWAS) findings to identify causal genes aids in elucidating the biological …
study (GWAS) findings to identify causal genes aids in elucidating the biological …
Genetic architecture of brain morphology and overlap with neuropsychiatric traits
Uncovering the genetic architectures of brain morphology offers valuable insights into brain
development and disease. Genetic association studies of brain morphological phenotypes …
development and disease. Genetic association studies of brain morphological phenotypes …