The importance of antimicrobial resistance in medical mycology
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
Candida auris Genetics and Emergence
A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Candida auris: Epidemiology, biology, antifungal resistance, and virulence
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …
auris is becoming a worldwide public health threat that has been attracting considerable …
Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …
along with significant agricultural crop loss caused by various fungal species, has resulted in …
Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare …
S Ahmad, W Alfouzan - Microorganisms, 2021 - mdpi.com
Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …
[HTML][HTML] The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris
Highlights•C. auris exhibits resistance to multiple antifungal agents and represents a public
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …
[HTML][HTML] Roles of Hsp90 in Candida albicans morphogenesis and virulence
Highlights•Hsp90 is a molecular chaperone that modulates the function of many client
proteins.•Morphogenesis is an important Candida albicans virulence trait.•Hsp90 regulates …
proteins.•Morphogenesis is an important Candida albicans virulence trait.•Hsp90 regulates …
The quiet and underappreciated rise of drug-resistant invasive fungal pathogens
A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug resistance
Candida auris is globally recognized as an opportunistic fungal pathogen of high concern,
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …