[HTML][HTML] Eosinophils in health and disease: a state-of-the-art review

ME Wechsler, A Munitz, SJ Ackerman, MG Drake… - Mayo Clinic …, 2021 - Elsevier
Eosinophils play a homeostatic role in the body's immune responses. These cells are
involved in combating some parasitic, bacterial, and viral infections and certain cancers and …

Food allergy: immune mechanisms, diagnosis and immunotherapy

W Yu, DMH Freeland, KC Nadeau - Nature Reviews Immunology, 2016 - nature.com
Food allergy is a pathological, potentially deadly, immune reaction triggered by normally
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …

Eosinophil depletion with benralizumab for eosinophilic esophagitis

ME Rothenberg, ES Dellon, MH Collins… - … England Journal of …, 2024 - Mass Medical Soc
Background Benralizumab is an eosinophil-depleting anti–interleukin-5 receptor α
monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic …

[HTML][HTML] Efficacy of dupilumab in a phase 2 randomized trial of adults with active eosinophilic esophagitis

I Hirano, ES Dellon, JD Hamilton, MH Collins… - Gastroenterology, 2020 - Elsevier
Background & Aims Eosinophilic esophagitis (EoE) is an allergen-mediated inflammatory
disease with no approved treatment in the United States. Dupilumab, a VelocImmune …

Food allergy: a practice parameter update—2014

HA Sampson, S Aceves, SA Bock, J James… - Journal of Allergy and …, 2014 - Elsevier
This parameter was developed by the Joint Task Force on Practice Parameters,
representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the …

ACG clinical guideline: evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE)

ES Dellon, N Gonsalves, I Hirano… - Official journal of the …, 2013 - journals.lww.com
Esophageal eosinophilia and eosinophilic esophagitis (EoE) are increasingly recognized
and prevalent conditions, which now represent common clinical problems encountered by …

World Health Organization‐defined eosinophilic disorders: 2019 update on diagnosis, risk stratification, and management

W Shomali, J Gotlib - American Journal of Hematology, 2019 - Wiley Online Library
Disease overview The eosinophilias encompass a broad range of non‐hematologic
(secondary or reactive) and hematologic (primary or clonal) disorders with potential for end …

Eosinophilic esophagitis

GT Furuta, DA Katzka - New England Journal of Medicine, 2015 - Mass Medical Soc
Eosinophilic esophagitis is an increasingly common diagnosis among children evaluated for
feeding problems and among adults with dysphagia and food impaction. This review …

Innate and adaptive immune responses in asthma

ST Holgate - Nature medicine, 2012 - nature.com
The recognition that asthma is primarily an inflammatory disorder of the airways associated
with T helper type 2 (TH2) cell-dependent promotion of IgE production and recruitment of …

Eosinophil knockout humans: uncovering the role of eosinophils through eosinophil-directed biological therapies

EA Jacobsen, DJ Jackson, E Heffler… - Annual review of …, 2021 - annualreviews.org
The enigmatic eosinophil has emerged as an exciting component of the immune system,
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …