Single-molecule localization microscopy (SMLM) is a relatively new imaging modality,
winning the 2014 Nobel Prize in Chemistry, and considered as one of the key super …

Single-molecule biophysics has transformed our understanding of biology, but also of the
physics of life. More exotic than simple soft matter, biomatter lives far from thermal …

Alpha-synuclein is known to bind to small unilamellar vesicles (SUVs) via its N terminus,
which forms an amphipathic alpha-helix upon membrane interaction. Here we show that …

Stone cells are the brachysclereid cells in pear (Pyrus) fruit, consisting almost entirely of
lignified secondary cell walls. They are distributed mainly near the fruit core and spread …

Clathrin-mediated endocytosis (CME) is a fundamental property of eukaryotic cells.
Classical CME proceeds via the formation of clathrin-coated pits (CCPs) at the plasma …

Retromer is a vital element of the endosomal protein sorting machinery and comprises two
subcomplexes that operate together to sort membrane proteins (cargo) and tubulate …

As proof-of-principle for generating superresolution structural information from DNA we
applied a method of localization microscopy utilizing photoblinking comparing intercalating …

Sarcomeres are extremely highly ordered macromolecular assemblies where structural
organization is intimately linked to their functionality as contractile units. Although the …

Super-resolution light microscopy, correlative light and electron microscopy, and volume
electron microscopy are revolutionising the way in which biological samples are examined …

Recently, it has been described that programmed cell death protein 1 (PD-1) overexpressing
melanoma cells are highly aggressive. However, until now it has not been defined which …