Adenoviral (Ad) vectors have emerged as a promising gene delivery platform for a variety of
therapeutic and vaccine purposes during last two decades. However, the presence of …

Classical swine fever (CSF) is an economically important highly contagious disease of
swine worldwide. Classical swine fever virus (CSFV) is its etiological agent, and the only …

Human adenoviral (HAd) vectors have demonstrated great potential as vaccine vectors.
Preclinical and clinical studies have demonstrated the feasibility of vector design, robust …

Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been
extensively studied in preclinical models and clinical trials over the past two decades …

Vaccination is one of the major achievements of modern medicine. As a result of
vaccination, diseases such as polio and measles have been controlled and small pox has …

Adenoviral (Ad) vectors can efficiently transduce a broad range of cell types and have been
used extensively in preclinical and clinical studies for gene delivery applications. The …

In this study, a molecular procedure for the detection of adenoviruses of animal origin was
developed to evaluate the level of excretion of these viruses by swine and cattle and to …

Adenovirus vectors have significant potential for long-or short-term gene transfer. Preclinical
and clinical studies using human derived adenoviruses (HAd) have demonstrated the …

Importance of the field: With the emergence of highly pathogenic avian influenza H5N1
viruses that have crossed species barriers and are responsible for lethal infections in …

Although recombinant human adenovirus (HAV)-based vectors offer several advantages for
somatic gene therapy and vaccination over other viral vectors, it would be desirable to …