Type 1 regulatory T (Tr1) cells, in addition to other regulatory cells, contribute to
immunological tolerance to prevent autoimmunity and excessive inflammation. Tr1 cells …

Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to
activate as much as 20% of the host T cells, which is why they were called superantigens …

Cow's milk allergy in children is often of short duration, which makes this disorder an
interesting clinical model for studies of tolerance to dietary antigens. Here, we studied T cell …

Little is known about the molecules that control the development and function of CD4+
CD25+ Tregs. Recently, it was shown that the transcription factor FOXP3 is necessary and …

Naturally occurring CD4+ regulatory T cells are generally identified through their expression
of CD25. However, in several experimental systems considerable T reg activity has been …

The underlying mechanisms of tumor-induced immune suppression need to be fully
understood. Regulatory T (Treg) cells have been shown to play an important role in tumor …

We previously reported that 4C8 monoclonal antibody (mAb) provides a costimulatory signal
to human CD4+ T cells and consequently induces regulatory T (Treg) cells, which are hypo …

Studies of mechanisms of disease regulation by CD4+ CD25+ regulatory T cells (Treg) have
been focused on their interaction with effector T cells; however, the possibility that regulation …

Cumulative evidence suggests the up-regulation of interleukin (IL)-10 and T-regulatory
(Treg) cells is implicated in anti-inflammatory effect of heme oxygenase-1 (HO-1). Thus, we …

Background Cannabidiol (CBD), the main non-psychoactive cannabinoid, has been
previously shown by us to ameliorate clinical symptoms and to decrease inflammation in …