Purpose The notion of what constitutes meaningful differences or changes in patient-
reported outcome scores is represented by meaningful change thresholds (MCTs). Applying …

Background Transthoracic minimally invasive esophagectomy (MIE) is increasingly
performed as part of curative multimodality treatment. There appears to be no robust …

PROBLEM IDENTIFICATION: This systematic review compared the efficacy of interventions
to usual care on adherence to oral anticancer regimens. LITERATURE SEARCH: Embase® …

Physical exercise both during and after curative cancer treatment has been shown to reduce
side effects. Evidence in the metastatic cancer setting is scarce, and interventions that …

Background The coronavirus disease 2019 (COVID-19) pandemic (officially declared on the
March 11, 2020), and the resulting measures, are impacting daily life and medical …

Background Breast cancer surgery in older women is variable and sometimes non-standard
owing to concerns about morbidity. Bridging the Age Gap in Breast Cancer is a prospective …

Background The European Society for Medical Oncology-Magnitude of Clinical Benefit
Scale (ESMO-MCBS) has been developed to grade clinical benefit of cancer therapies …

Abstract Background Minimally important differences (MIDs) allow interpretation of the
clinical relevance of health-related quality of life (HRQOL) results. This study aimed to …

Background The aim of the study was to estimate the minimally important difference (MID)
for interpreting group-level change over time, both within a group and between groups, for …

Abstract Aim The European Organisation for Research and Treatment of Cancer Quality of
Life Questionnaire Core 30 (EORTC QLQ‐C30) assesses the health‐related quality of life of …