Desmoid tumors: a comprehensive review

M Bektas, T Bell, S Khan, B Tumminello… - Advances in …, 2023 - Springer
Desmoid tumors (DT) are rare, locally aggressive, fibroblastic soft-tissue tumors that are
characterized by infiltrative growth and can affect organs and adjacent structures, resulting …

Evolving strategies for management of desmoid tumor

RF Riedel, M Agulnik - Cancer, 2022 - Wiley Online Library
Desmoid tumors (DTs) are rare soft tissue mesenchymal neoplasms that may be associated
with impairments, disfigurement, morbidity, and (rarely) mortality. DT disease course can be …

Nirogacestat, a γ-secretase inhibitor for desmoid tumors

M Gounder, R Ratan, T Alcindor… - … England Journal of …, 2023 - Mass Medical Soc
Background Desmoid tumors are rare, locally aggressive, highly recurrent soft-tissue tumors
without approved treatments. Methods We conducted a phase 3, international, double-blind …

Desmoid-type fibromatosis: Current therapeutic strategies and future perspectives

R Ibrahim, T Assi, R Khoury, C Ngo, M Faron… - Cancer Treatment …, 2024 - Elsevier
Desmoid tumors (DT) are rare, slow-growing, locally invasive soft tissue tumors that often
pose significant therapeutic challenges. Traditional management strategies including active …

The Notch signaling pathway in desmoid tumor: recent advances and the therapeutic prospects

C Zheng, J Huang, G Xu, W Li, X Weng… - Biochimica et Biophysica …, 2024 - Elsevier
Desmoid tumor (DT) is a rare fibroblastic soft-tissue neoplasm that is characterized by local
aggressiveness but no metastatic potential. Although the prognosis is relatively favorable …

MR-guided focused ultrasound therapy of extra-abdominal desmoid tumors: a multicenter retrospective study of 105 patients

DM Düx, JD Baal, R Bitton, J Chen, RL Brunsing… - European …, 2024 - Springer
Objective To assess the safety and efficacy of magnetic resonance-guided focused
ultrasound (MRgFUS) for the treatment extra-abdominal desmoids. Methods A total of 105 …

Examining nirogacestat for adults with progressing desmoid tumors who require systemic treatment

F Campos, B Kasper - Expert Opinion on Pharmacotherapy, 2024 - Taylor & Francis
Introduction Desmoid tumor (DT) is a rare, locally aggressive, mesenchymal neoplasm that
can arise at any site in the body. Medical therapies play a major role for DT's patients …

Capturing Patient Voice to Improve Outcomes That Matter to Patients with Desmoid Tumor

B Kasper, M Gounder, L Hernandez… - Cancer Management …, 2024 - Taylor & Francis
Desmoid tumors (DT) are rare, intermediate-grade sarcomas characterized by locally
aggressive growths that commonly occur intra-abdominally, in the abdominal wall, or in the …

Desmoid Fibromatosis of the Anterior Abdominal Wall in Pregnancy: A Case Report and Review of the Literature

P Zubor, CM Henriksen, ME Økstad, E Cerskuviene… - Diseases, 2024 - mdpi.com
A desmoid tumor (DT) is a rare benign neoplasm arising from muscle aponeurosis,
associated mostly with trauma or pregnancy. DT has an infiltrative and locally aggressive …

Disease and economic burden of surgery in desmoid tumors: a review

MM Fernandez, T Bell, B Tumminello… - Expert Review of …, 2023 - Taylor & Francis
Introduction Desmoid tumors (DT) are soft-tissue tumors that infiltrate into surrounding
structures with ill-defined margins. Although surgery is a potential treatment option, complete …