Medicinal chemistry is still clearly dominated by organic chemistry. Most of the marketed
drugs are purely organic molecules. The right-hand neighbors of carbon in the periodic …

What is boron? The question itself may not seem very significant to many people. Their
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …

Icosahedral carboranes constitute a class of structurally unique molecules with exceptionally
thermal and chemical stabilities, which limits the derivatization of these clusters. In view of …

We have found the first reaction of direct cupration of fluoroform, the most attractive CF3
source for the introduction of the trifluoromethyl group into organic molecules. Treatment of …

We report the development of a new class of phosphorescent zwitterionic bis (heteroleptic) Ir
(III) compounds containing pyridyl ligands with weakly coordinating nido-carboranyl …

Metal-catalyzed mono-acylmethylation of pyridylcarboranes has been realized using α-
carbonyl sulfoxonium ylides as a coupling partner. The reaction features high efficiency …

Abstract Background: Carboranes (dicarba-closo-dodecaboranes) are a class of carbon-
containing polyhedral boron-cluster compounds having remarkable thermal stability and …

Introduction. The carboranes (dicarba-closo-dodecaboranes) 1 exhibit remarkable thermal
stability, are resistant to attack by most types of reagents, and are generally biologically …

The ability of ortho-, meta-and para-carboranes to enhance the emission intensity has been
compared. For this purpose a series of carborane-appended 1, 3, 5-triphenylbenzene (TB) …

Selective agonism of the estrogen receptor (ER) subtypes, ERα and ERβ, has historically
been difficult to achieve due to the high degree of ligand-binding domain structural similarity …