Research progress in the molecular mechanisms, therapeutic targets, and drug development of idiopathic pulmonary fibrosis

H Ma, X Wu, Y Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Recent studies have
identified the key role of crosstalk between dysregulated epithelial cells, mesenchymal …

Progress in understanding and treating idiopathic pulmonary fibrosis: Recent insights and emerging therapies

H Guo, J Sun, S Zhang, Y Nie, S Zhou… - Frontiers in …, 2023 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a long-lasting, continuously advancing, and irrevocable
interstitial lung disorder with an obscure origin and inadequately comprehended …

Syndrome of combined pulmonary fibrosis and emphysema: an official ATS/ERS/JRS/ALAT research statement

V Cottin, M Selman, Y Inoue, AW Wong… - American journal of …, 2022 - atsjournals.org
Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …

Impact of allergic rhinitis and asthma on COVID-19 infection, hospitalization, and mortality

J Ren, W Pang, Y Luo, D Cheng, K Qiu, Y Rao… - The Journal of Allergy …, 2022 - Elsevier
Background It remains unclear if patients with allergic rhinitis (AR) and/or asthma are
susceptible to corona virus disease 2019 (COVID-19) infection, severity, and mortality …

Air pollutants, genetic susceptibility and risk of incident idiopathic pulmonary fibrosis

F Cui, Y Sun, J Xie, D Li, M Wu, L Song… - European …, 2023 - Eur Respiratory Soc
Background Air pollutants are considered as non-negligible risk factors of idiopathic
pulmonary fibrosis (IPF). However, the relationship between long-term air pollution and the …

Tobacco smoking is associated with combined pulmonary fibrosis and emphysema and worse outcomes in interstitial lung disease

D Douglas, L Keating, R Strykowski… - … of Physiology-Lung …, 2023 - journals.physiology.org
Tobacco smoking is an established cause of pulmonary disease whose contribution to
interstitial lung disease (ILD) is incompletely characterized. We hypothesized that compared …

Incidence and prevalence of interstitial lung diseases worldwide: a systematic literature review

RS Gupta, A Koteci, A Morgan… - BMJ Open …, 2023 - bmjopenrespres.bmj.com
Interstitial lung disease (ILD) is a collective term representing a diverse group of pulmonary
fibrotic and inflammatory conditions. Due to the diversity of ILD conditions, paucity of …

The genetic landscape of familial pulmonary fibrosis

Q Liu, Y Zhou, JD Cogan, DB Mitchell… - American Journal of …, 2023 - atsjournals.org
Rationale and Objectives: Up to 20% of idiopathic interstitial lung disease is familial, referred
to as familial pulmonary fibrosis (FPF). An integrated analysis of FPF genetic risk was …

Trials and treatments: an update on pharmacotherapy for idiopathic pulmonary fibrosis

L Thong, EJ McElduff, MT Henry - Life, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrosing interstitial lung
disease that occurs predominantly in the older population. There is increasing incidence …

Impact of smoking on the development of idiopathic pulmonary fibrosis: results from a nationwide population-based cohort study

W Bae, CH Lee, J Lee, YW Kim, K Han, SM Choi - Thorax, 2022 - thorax.bmj.com
Background Smoking has been considered an important risk factor for idiopathic pulmonary
fibrosis (IPF) incidence. However, there are no population-based large-scale studies …