Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems

C Schneider, R Langer, D Loveday, D Hair - Journal of Controlled Release, 2017 - Elsevier
The potential for use of polymers in controlled drug delivery systems has been long
recognized. Since their appearance in the literature, a wide range of degradable and non …

Hot-melt extruded pharmaceutical dosage form

L Barnscheid, E Galia - US Patent 10,080,721, 2018 - Google Patents
The invention relates to a hot-melt extruded pharmaceutical dosage form with controlled
release of a pharmacologically active ingredient (A) embedded in a matrix comprising a …

Dosage form with impeded abuse

E Arkenau-Marić, J Bartholomaeus, I Ziegler… - US Patent …, 2014 - Google Patents
(57) ABSTRACT A multiparticulate dosage form formulated to make misuse more di? icult
containing least one active substance with potential for misuse (A), at least one synthetic or …

Tamper resistant dosage form with bimodal release profile

L Barnscheid, A Geiβler, K Wening, S Strauch… - US Patent …, 2017 - Google Patents
The invention relates to a pharmaceutical dosage form comprising (i) at least one formed
segment (S.), which contains a first pharmacologically active ingredient (AI) and provides …

Tamper-resistant tablet providing immediate drug release

S Schwier, M Haupts, L Barnscheid, J Pätz - US Patent 10,201,502, 2019 - Google Patents
4, 764, 378 A 4, 765, 989 A 4, 774, 074 A 4, 774, 092 A 4, 783, 337 A 4, 806, 337 A RE33,
093 E 4, 880, 585 A 4, 892, 778 A 4, 892, 889 A 4, 940, 556 A 4, 954, 346 A 4, 957, 668 A 4 …

Sintering of wax for controlling release from pellets

R Singh, SS Poddar, A Chivate - Aaps Pharmscitech, 2007 - Springer
The purpose of the present study was to investigate incorporation of hydrophobic (ie, waxy)
material into pellets using a thermal sintering technique and to evaluate the pellets in vitro …

Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc

L Barnscheid, E Galia, A Geissler, J Pätz… - US Patent …, 2018 - Google Patents
(57) ABSTRACT A thermoformed, tamper-resistant pharmaceutical dosage form comprises:
a) a pharmacologically active ingredient; b) a polyalkylene oxide having a weight average …

Tamper-resistant dosage form containing one or more particles

L Barnscheid, A Geiβler, K Wening, J Pätz - US Patent 10,154,966, 2018 - Google Patents
US10154966B2 - Tamper-resistant dosage form containing one or more particles - Google
Patents US10154966B2 - Tamper-resistant dosage form containing one or more particles …

Tamper-resistant dosage form containing ethylene-vinyl acetate polymer

K Wening, L Barnscheid, S Schwier… - US Patent …, 2020 - Google Patents
The invention relates to a tamper-resistant, oral pharmaceu tical dosage form comprising a
pharmacologically active ingredient having psychotropic action and an ethylene-vinyl …

Crush resistant delayed-release dosage forms

E Arkenau-Marić, J Bartholomäus… - US Patent …, 2020 - Google Patents
The invention relates to a dosage form comprising a physiologically effective amount of a
physiologically active substance (A), a synthetic, semi-synthetic or natural polymer (C) …