[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

[HTML][HTML] Does vitamin C influence neurodegenerative diseases and psychiatric disorders?

J Kocot, D Luchowska-Kocot, M Kiełczykowska, I Musik… - Nutrients, 2017 - mdpi.com
Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis

MD Wang, J Little, J Gomes, NR Cashman, D Krewski - Neurotoxicology, 2017 - Elsevier
Although amyotrophic lateral sclerosis (ALS) was identified as a neurological condition 150
years ago, risk factors related to the onset and progression of ALS remain largely unknown …

The neuroprotective potential of carotenoids in vitro and in vivo

J Manochkumar, CGP Doss, HR El-Seedi, T Efferth… - Phytomedicine, 2021 - Elsevier
Background Despite advances in research on neurodegenerative diseases, the
pathogenesis and treatment response of neurodegenerative diseases remain unclear …

Ascorbic acid: its role in immune system and chronic inflammation diseases

A Sorice, E Guerriero, F Capone… - Mini reviews in …, 2014 - ingentaconnect.com
Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing
the scurvy disease, and became very popular for its antioxidant properties. It is an important …

[HTML][HTML] Lipid peroxidation and antioxidant supplementation in neurodegenerative diseases: a review of human studies

S Petrovic, A Arsic, D Ristic-Medic, Z Cvetkovic, V Vucic - Antioxidants, 2020 - mdpi.com
Being characterized by progressive and severe damage in neuronal cells,
neurodegenerative diseases (NDDs) are the major cause of disability and morbidity in the …

[HTML][HTML] Old things new view: ascorbic acid protects the brain in neurodegenerative disorders

A Covarrubias-Pinto, AI Acuña, FA Beltrán… - International journal of …, 2015 - mdpi.com
Ascorbic acid is a key antioxidant of the Central Nervous System (CNS). Under brain activity,
ascorbic acid is released from glial reservoirs to the synaptic cleft, where it is taken up by …

Recent advances in studies on the therapeutic potential of dietary carotenoids in neurodegenerative diseases

KS Cho, M Shin, S Kim, SB Lee - Oxidative medicine and …, 2018 - Wiley Online Library
Carotenoids, symmetrical tetraterpenes with a linear C40 hydrocarbon backbone, are
natural pigment molecules produced by plants, algae, and fungi. Carotenoids have …

[HTML][HTML] Oxidative stress, the blood–brain barrier and neurodegenerative diseases: The critical beneficial role of dietary antioxidants

J Feng, Y Zheng, M Guo, I Ares, M Martínez… - … Pharmaceutica Sinica B, 2023 - Elsevier
In recent years, growing awareness of the role of oxidative stress in brain health has
prompted antioxidants, especially dietary antioxidants, to receive growing attention as …

[HTML][HTML] Metabolic abnormalities, dietary risk factors and nutritional management in amyotrophic lateral sclerosis

E D'Amico, G Grosso, JW Nieves, A Zanghì… - Nutrients, 2021 - mdpi.com
Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative
disease that affects motor neurons, leading to a relentless paralysis of skeletal muscles and …