Raman spectroscopy is increasingly commonly used to understand how changes in bone
composition and structure influence tissue-level bone mechanical properties. The …

Although indentation experiments have long been used to measure the hardness and
Young's modulus, the utility of this technique in analyzing the complete elastic–plastic …

In patients with breast cancer, lower bone mineral density increases the risk of bone
metastasis. Although the relationship between bone-matrix mineralization and tumour-cell …

Bones provide mechanical and protective function, while also serving as housing for marrow
and a site for regulation of calcium ion homeostasis. The properties of bones do not remain …

The present overview is intended to point the readers' attention to the important subject of
calcium orthophosphates (CaPO 4). This type of materials is of the special significance for …

Background Progress in the diagnosis and prediction of fragility fractures depends on
improvements to the understating of the compositional contributors of bone quality to …

The present overview is intended to point the readers' attention to the important subject of
calcium orthophosphates. This type of materials is of special significance for human beings …

Background The skeleton plays a critical structural role in bearing functional loads, and
failure to do so results in fracture. As we evaluate new therapeutics and consider treatments …

The extracellular matrix (ECM) consists of a complex mesh of proteins, glycoproteins, and
glycosaminoglycans, and is essential for maintaining the integrity and function of biological …

Raman spectroscopy (RS) is used to analyze the physiochemical properties of bone
because it is non-destructive and requires minimal sample preparation. With over two …