Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

Natural killer (NK) cells belong to the innate immune system and contribute to protecting the
host through killing of infected, foreign, stressed or transformed cells. Additionally, via …

Natural killer (NK) cells kill infected, transformed and stressed cells when an activating NK
cell receptor is triggered. Most NK cells and some innate lymphoid cells express the …

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

Conventional type 1 dendritic cells (cDC1) are critical for antitumor immunity, and their
abundance within tumors is associated with immune-mediated rejection and the success of …

Natural killer (NK) cells are a population of innate lymphoid cells playing a pivotal role in
host immune responses against infection and tumor growth. These cells have a powerful …

Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second
messenger that binds and activates the adaptor protein STING, which leads to interferon …

The past decade of cancer research has been marked by a growing appreciation of the role
of immunity in cancer. Mutations in the tumour genome can cause tumours to express …

The metastatic spread of malignant cells to distant anatomical locations is a prominent
cause of cancer-related death. Metastasis is governed by cancer-cell-intrinsic mechanisms …

Chronic inflammation increases the risk of several cancers, including gastric, colon, and
hepatic cancers. Conversely, tumors, similar to tissue injury, trigger an inflammatory …