Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Ample evidence exists in support of the potent anti-inflammatory properties of statins. In cell
studies and animal models statins exert beneficial cardiovascular effects. By inhibiting …

Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and
its antiatherogenic properties support cardiovascular homeostasis. Diminished NO …

Nitric oxide (NO) is generated endogenously by NO synthases to regulate a number of
physiological processes including cardiovascular and metabolic functions. A decrease in the …

The endothelium is the orchestral conductor of blood vessel function. Pathological blood
vessel formation (a process termed pathological angiogenesis) or the inability of endothelial …

The impact of statin therapy on plasma asymmetric dimethylarginine (ADMA) levels has not
been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of …

Chronic inflammation enhances the detrimental role of dyslipidaemia during atherogenesis.
Statins are among the most effective anti-atherosclerotic medications, being able to impact …

The small free radical gas nitric oxide (NO) plays a key role in various physiological and
pathological processes through enhancement of endothelial cell survival and proliferation …

Purpose Inflammation participates centrally in all stages of atherosclerosis (AS), which
begins with pro-inflammatory processes and inflammatory changes in the endothelium …

Airway remodeling in asthma contributes to airway hyperreactivity, loss of lung function, and
persistent symptoms. Current therapies do not adequately treat the structural airway …