Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Proton pump inhibitors (PPIs), such as omeprazole, lansoprazole, rabeprazole,
esomeprazole, and pantoprazole, are mainly metabolized by CYP2C19 in the liver. There …

Background. Asthma, a serious health problem worldwide, is becoming more common.
Colonization with Helicobacter pylori, a major human indigenous (commensal) microbe …

Helicobacter pylori has apparently colonized the human stomach since time immemorial
and is superbly adapted for persistence. Several genotypes, including cag+, are associated …

The recognition of gastritis due to Helicobacter pylori as a factor of major importance has
revolutionized the therapeutic approach to peptic ulcer disease. 1, 2 The recurrence of …

Across populations of children, Helicobacter pylori prevalence ranges from under 10% to
over 80%. Low prevalence occurs in the US, Canada, and northern and western Europe; …

In addition to erythromycin, macrolides now available in the United States include
azithromycin and clarithromycin. These two new macrolides are more chemically stable and …

Background: Omeprazole is metabolized by S-mephenytoin 4′-hydroxylase (CYP2C19) in
the liver. In persons with a poor-metabolizer genotype for CYP2C19, the therapeutic efficacy …

The microbes that persistently colonise their vertebrate hosts are not accidental. 1 Although
highly numerous and diverse, there is specificity by site and substantial conservation …

Aim: To prospectively assess the antibacterial resistance rate in Helicobacter pylori strains
obtained from symptomatic children in Europe. Methods: During a 4-year period, 17 …