WNT-signaling controls important cellular processes throughout embryonic development
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …

Liquid–liquid phase separation (LLPS) is now recognized as a common mechanism
underlying regulation of enzyme activity in cells. Insights from studies in cells are …

Enzymes within a family often catalyze different reactions. In some cases, this variety stems
from different catalytic machinery, but in other cases, the machinery is identical; …

Salicylic acid (SA) is an important mediator of plant defense response. In Arabidopsis
(Arabidopsis thaliana), this compound was proposed to derive mainly from isochorismate …

Carbon–carbon bond formation is the key reaction for organic synthesis to construct the
carbon framework of organic molecules. The review gives a selection of biocatalytic C–C …

Abstract The 1, 4-naphthoquinones (1, 4-NQs) are a diverse group of natural products found
in every kingdom of life. Plants, including many horticultural species, collectively synthesize …

Despite the astonishing breadth of enzymes in nature, no enzymes are known for many of
the valuable catalytic transformations discovered by chemists. Recent work in enzyme …

Sequential enzymes in a biosynthetic pathway often self-assemble to form nanomachineries
known as multienzyme complexes inside cells. Enzyme self-assembly insulates toxic …

The genus Mycobacterium comprises a group of obligately aerobic bacteria that have
adapted to inhabit a wide range of intracellular and extracellular environments …

The emergence of bacteria that are resistant to several antibiotics has represented a serious
hazard to human health globally. Bioactive metabolites from medicinal plants have a wide …