BACKGROUND Uterine natural killer cells (uNK) are the most abundant lymphocytes found
in the decidua during implantation and in first trimester pregnancy. They are important for …

Pregnancy is a unique type of immunological process. Healthy pregnancy is associated with
a series of inflammatory events: implantation (inflammation), gestation (anti-inflammation) …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …

Avoiding the immune rejection of transplanted T cells is central to the success of allogeneic
cancer immunotherapies. One solution to protecting T-cell grafts from immune rejection …

The maternal-fetal interface undergoes dynamic changes to allow the fetus to grow and
develop in the uterus, despite being recognized by the maternal immune cells. Within the …

During pregnancy, semiallogeneic fetal extravillous trophoblasts (EVT) invade the uterine
mucosa without being rejected by the maternal immune system. Several mechanisms were …

An improved mechanistic understanding of the adaptational processes mounted during
mammalian reproduction is emerging. Intricate pathways occurring at the fetomaternal …

The success of checkpoint blockade therapy revolutionized cancer treatment. However, we
need to increase the fraction of responding patients and overcome acquired resistance to …

Macrophages (MФs) are the leukocytes produced from differentiation of monocytes and are
located in almost all tissues of human body. They are involved in various processes, such as …