[HTML][HTML] Myasthenia gravis: epidemiology, pathophysiology and clinical manifestations
L Dresser, R Wlodarski, K Rezania… - Journal of clinical medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neurological disorder characterized by defective
transmission at the neuromuscular junction. The incidence of the disease is 4.1 to 30 cases …
transmission at the neuromuscular junction. The incidence of the disease is 4.1 to 30 cases …
Myasthenia gravis: subgroup classification and therapeutic strategies
NE Gilhus, JJ Verschuuren - The Lancet Neurology, 2015 - thelancet.com
Myasthenia gravis is an autoimmune disease that is characterised by muscle weakness and
fatigue, is B-cell mediated, and is associated with antibodies directed against the …
fatigue, is B-cell mediated, and is associated with antibodies directed against the …
[HTML][HTML] The neuromuscular junction in health and disease: molecular mechanisms governing synaptic formation and homeostasis
PM Rodríguez Cruz, J Cossins, D Beeson… - Frontiers in molecular …, 2020 - frontiersin.org
The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
[HTML][HTML] Autoantibody specificities in myasthenia gravis; implications for improved diagnostics and therapeutics
K Lazaridis, SJ Tzartos - Frontiers in immunology, 2020 - frontiersin.org
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness and
fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by …
fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by …
Myasthenia gravis—autoantibody characteristics and their implications for therapy
NE Gilhus, GO Skeie, F Romi, K Lazaridis… - Nature reviews …, 2016 - nature.com
Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies that target the
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …
Neuromuscular junction formation, aging, and disorders
Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
[HTML][HTML] Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting
LA Tintignac, HR Brenner… - Physiological …, 2015 - journals.physiology.org
The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
[HTML][HTML] Drugs that induce or cause deterioration of myasthenia gravis: an update
S Sheikh, U Alvi, B Soliven, K Rezania - Journal of Clinical Medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder which is characterized
by presence of antibodies against acetylcholine receptors (AChRs) or other proteins of the …
by presence of antibodies against acetylcholine receptors (AChRs) or other proteins of the …
[HTML][HTML] Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society
Myasthenia gravis (MG) is an autoimmune antibody-mediated disorder of neuromuscular
synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and …
synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and …
Advances in the understanding of disease mechanisms of autoimmune neuromuscular junction disorders
MG Huijbers, A Marx, JJ Plomp, R Le Panse… - The Lancet …, 2022 - thelancet.com
Muscle weakness and fatigue are the hallmarks of autoimmune neuromuscular junction
disorders. Although a plethora of immunosuppressive treatments exist, no cure is available …
disorders. Although a plethora of immunosuppressive treatments exist, no cure is available …