Treatment of cancer with allogeneic natural killer (NK) cell therapies has seen rapid
development, especially use against hematologic malignancies. Clinical trials of NK cell …

Natural killer (NK) cells are potent cytotoxic effector cells for cancer therapy and potentially
for severe viral infections. However, there are technical challenges to obtain sufficient …

Natural killer (NK) cells can induce an antigen-independent immune response against
malignant cells. A growing number of scientific reports and clinical studies have shown …

Natural killer (NK) cells are attractive within adoptive transfer settings in cancer
immunotherapy due to their potential for allogeneic use; their alloreactivity is enhanced …

Immunotherapy based on natural killer (NK) cells is a promising approach for treating a
variety of cancers. Unlike T cells, NK cells recognize target cells via a major …

Adoptive cell therapy has received a great deal of interest in the treatment of advanced
cancers that are resistant to traditional therapy. The tremendous success of chimeric antigen …

Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

Natural killer (NK) cells play a crucial role in host immunity by detecting cells that
downregulate MHC class I presentation and upregulate stress ligands, as commonly seen in …

Natural killer (NK) cells are part of the innate immune system and represent the first line of
defense against infections and tumors. In contrast to T cells, NK cells do not require prior …

Natural killer (NK) cells recognize targets stressed by malignant transformation or infection
(particularly CMV). We now know that NK cells can be long-lived and remember past …