The Edinger‐Westphal nucleus: A historical, structural, and functional perspective on a dichotomous terminology

T Kozicz, JC Bittencourt, PJ May… - Journal of …, 2011 - Wiley Online Library
The eponymous term nucleus of Edinger‐Westphal (EW) has come to be used to describe
two juxtaposed and somewhat intermingled cell groups of the midbrain that differ …

Stress, motivation, and the gut–brain axis: a focus on the ghrelin system and alcohol use disorder

LS Morris, V Voon, L Leggio - Alcoholism: Clinical and …, 2018 - Wiley Online Library
Since its discovery, the gut hormone, ghrelin, has been implicated in diverse functional roles
in the central nervous system. Central and peripheral interactions between ghrelin and other …

Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin‐containing neurons

S Kaur, AE Ryabinin - Alcoholism: Clinical and Experimental …, 2010 - Wiley Online Library
Background: The current therapies for alcohol abuse disorders are not effective in all
patients, and continued development of pharmacotherapies is needed. One approach that …

Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the …

JP Schroeder, M Spanos, JR Stevenson, J Besheer… - …, 2008 - Elsevier
Relapse to alcohol use after periods of abstinence is a hallmark behavioral pathology of
alcoholism and a major clinical problem. Emerging evidence indicates that metabotropic …

Anterior cingulate cortex contributes to alcohol withdrawal-induced and socially transferred hyperalgesia

ML Smith, AT Walcott, MM Heinricher, AE Ryabinin - Eneuro, 2017 - eneuro.org
Pain is often described as a “biopsychosocial” process, yet social influences on pain and
underlying neural mechanisms are only now receiving significant experimental attention …

Neuroplasticity in brain reward circuitry following a history of ethanol dependence

AC Hansson, R Rimondini… - European Journal of …, 2008 - Wiley Online Library
Mitogen‐activated and extracellular regulated kinase (MEK) and extracellular signal‐
regulated protein kinase (ERK) pathways may underlie ethanol‐induced neuroplasticity …

The centrally projecting Edinger–Westphal nucleus—I: Efferents in the rat brain

EDDS Júnior, AV Da Silva, KRT Da Silva… - Journal of chemical …, 2015 - Elsevier
The oculomotor accessory nucleus, often referred to as the Edinger–Westphal nucleus [EW],
was first identified in the 17th century. Although its most well known function is the control of …

On the role of urocortin 1 in the non-preganglionic Edinger–Westphal nucleus in stress adaptation

T Kozicz - General and comparative endocrinology, 2007 - Elsevier
The discovery of novel members of the CRF neuropeptide family, urocortin 1 (Ucn1),
urocortin 2 and 3 has provided important insights into stress adaptation pathways, and …

Gene expression induced by drugs of abuse

JS Rhodes, JC Crabbe - Current Opinion in Pharmacology, 2005 - Elsevier
The transition from infrequent drug use to addiction (ie the loss of control over consumption
of a drug) probably involves changes in gene expression that restructure neural circuits in …

Prairie voles as a novel model of socially facilitated excessive drinking

AMJ Anacker, JM Loftis, S Kaur… - Addiction biology, 2011 - Wiley Online Library
Social relationships strongly affect alcohol drinking in humans. Traditional laboratory
rodents do not exhibit social affiliations with specific peers, and cannot adequately model …