Curcumin, a natural polyphenolic compound extracted from rhizomes of Curcuma longa
(turmeric), a plant in the ginger family (Zingiberaceae) has been used worldwide and …

Parkinson's disease (PD) is an age‑related complex neurodegenerative disease that
affects≤ 80% of dopaminergic neurons in the substantia nigra pars compacta (SNpc). It has …

Exposure to rotenone leads to parkinsonian features, such as loss of dopaminergic neurons
in the substantia nigra and motor impairment, however, the validity of this model has recently …

Melatonin treatment showed a potent neuroprotective action in experimental models and in
clinical studies. However, the entire disease prevention is not observed with melatonin …

Rotenone, a naturally occurring and commonly used pesticide, has been established as a
model for inducing Parkinson's Disease (PD) in rodents. Kolaviron is a biflavonoid complex …

Neurotoxin exposure of zebrafish larvae has been used to mimic a Parkinson's disease (PD)
phenotype and to facilitate high-throughput drug screening. However, the vulnerability of …

Rotenone, a commonly used pesticide, is well documented to induce selective degeneration
in dopaminergic neurons and motor dysfunction. Such rotenone-induced neurodegenration …

Rotenone, a pesticide, causes neurotoxicity via the mitochondrial complex-I inhibition. The
present study was conducted to evaluate the role of endoplasmic reticulum (ER) stress in …

Oxidative stress and neuroinflammation play key roles in the initiation and progression of
Parkinson's disease (PD), a neurodegenerative disorder, associated with the loss of …

Withania somnifera (Ashwagandha, WS) or Indian ginseng possesses multiple
pharmacological properties which are mainly attributed to the active constituents …