Mitochondria are one of the basic essential components for eukaryotic life survival. It is also
the source of respiratory ATP. Recently published studies have demonstrated that …

Introduction Cystic fibrosis (CF) is a life-threatening inherited disease caused by mutations
in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, an …

Rationale: Elexacaftor, tezacaftor, and ivacaftor (ETI) in triple combination improves
pulmonary health for people with cystic fibrosis (PwCF). However, its impact on objective …

Background The potentiator ivacaftor (VX-770) has been approved for therapy of 38 cystic
fibrosis (CF) mutations (∼ 10% of the patient population) associated with a gating defect of …

Abstract Ethnopharmacological relevance Resina Draconis (RD) is the red resin of
Dracaena cochinchinensis (Lour.) SC Chen and most used as a hemostatic drug in …

Cystic fibrosis (CF) is a genetic disease associated to mutations in the cystic fibrosis
transmembrane conductance regulator gene, which results in the alteration of biological …

Introduction Hypoxia due to sinus obstruction is a major pathogenic mechanism leading to
sinusitis. The objective of the current study is to define the electrophysiologic characteristics …

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic
fibrosis transmembrane conductance regulator (CFTR) gene, responsible for the synthesis …

Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB)
and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a …

Background Abnormal chloride (Cl–) transport dehydrates airway surface liquid (ASL) in
sinonasal epithelium leading to mucus stasis and chronic rhinosinusitis. As an experimental …