Biologically active compounds play a very important role in our daily life. Almost all
biologically active compounds contain heteroatoms and among these, a major portion is …

Solid-phase organic synthesis is a powerful tool in the synthesis of small organic molecules
and building of libraries of compounds for drug discovery. Heterocyclic compounds are …

Herein, we report the discovery and structure–activity relationships of 5-substituted-2-[(3, 5-
dinitrobenzyl) sulfanyl]-1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles as a new class of …

The synthesis of benzimidazole linked oxadiazole derivatives designed as potential EGFR
and erbB2 receptor inhibitors with anticancer and apoptotic activity were studied …

Agonists of benzodiazepine (BZD) binding site in GABA receptors are widely used in clinical
practice. In spite of their benefits they have several side effects, so synthesis of new agonists …

Two novel series of N4-(5-(2/3/4-substituted-phenyl)-1, 3, 4-oxadiazol-2-yl)-N1-(2-methyl-5-
(prop-1-en-2-yl) cyclohex-2-enylidene) semicarbazide and N4-(5-(2/3/4-substituted-phenyl) …

Abstract A series of novel 1-[5-(4-methoxy-phenyl)-[1, 3, 4] oxadiazol-2-yl]-piperazine
derivatives 8 (a–o) were synthesized and characterized by elemental analyses, 1 H NMR …

A series of 2-(benzylthio)-5-aryloxadiazole derivatives have been designed and
synthesized, and their biological activities are also evaluated for EGFR inhibitory activity …

Parkinson's disease (PD) is a progressive neurological condition that causes tremors,
rigidity and postural instability. In addition, it can lead to complications such as constipation …

A series of novel N1-{5-[(naphthalene-2-yloxy) methyl]-1, 3, 4-oxadiazol-2-yl}-N4-(4-
substitutedbenzaldehyde)-semicarbazone, N1-{5-[(naphthalene-2-yloxy) methyl]-1, 3, 4 …