Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a
global health issue. A comprehensive understanding of the different molecular mechanisms …

Accumulating evidences demonstrate that long-term exposure to atmospheric fine particles
and air pollutants elevates the risk of chronic obstructive pulmonary disease (COPD) …

Autophagy is the key process by which the cell degrades parts of itself within the lysosomes.
It maintains cell survival and homeostasis by removing molecules (particularly proteins) …

Autophagy is an evolutionarily conserved cellular system crucial for cellular homeostasis
that protects cells from a broad range of internal and extracellular stresses. Autophagy …

Chronic obstructive pulmonary disease (COPD) is characterized by irreversible deterioration
of the airway wall. Cigarette smoking is the major trigger, and in vitro studies showed that …

Rationale Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, has been
considered as an important regulator for immune diseases. We have previously shown that …

Inflammation represents a fundamental immune response triggered by various detrimental
stimuli, such as infections, tissue damage, toxins, and foreign substances. Protein …

Our paper describes the production and characterization of inhalable microparticles loaded
with nanoparticles for the lung administration of rapamycin (Rapa). In detail, core–shell …

The accumulation of senescent cells drives inflammaging and increases morbidity of chronic
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …