Mannan-binding lectin (MBL) is a plasma protein found in association with several serine
proteases (MASPs) forming the MBL complex. MBL recognises carbohydrate structures …

A classical function of C1q is to bind immune complexes and initiate complement activation
producing membrane lytic complexes, opsonins and anaphylatoxins. This classical pathway …

Mannan-binding lectin (MBL), a member of the collectin family, is known to have opsonic
function, although identification of its cellular receptor has been elusive. Complement C1q …

BACKGROUND & AIMS: Complement is involved in the development of alcoholic liver
disease in mice; however, the mechanisms for complement activation during ethanol …

Advances in immunosuppression have decreased the incidence of acute rejection, but the
development of vasculopathy in the coronary arteries of transplants continues to limit the …

Review on the role for C1q in enhancement of phagocytosis, specifically focusing on C1q-
mediated clearance of apoptotic cells. Complement component C1q is a member of a family …

Conflicting data have emerged regarding the role of complement activation in the
pathophysiology of cerebral ischemia. On the basis of considerable evidence implicating …

Dramatic progress has been achieved during the past year in our understanding of how the
complement system is activated via the mannan-binding-lectin pathway. Surprising …

Maturation of dendritic cells (DCs) is known to be induced by several stimuli, including
microbial products, inflammatory cytokines and immobilized IgG, as demonstrated recently …

Deficiency of mannose-binding lectin (MBL) is probably the most common human
immunodeficiency and is associated with an increased risk of mucosally acquired infections …