DockingGA: enhancing targeted molecule generation using transformer neural network and genetic algorithm with docking simulation

C Gao, W Bao, S Wang, J Zheng, L Wang… - Briefings in …, 2024 - academic.oup.com
Generative molecular models generate novel molecules with desired properties by
searching chemical space. Traditional combinatorial optimization methods, such as genetic …

[HTML][HTML] BO-DNA: Biologically optimized encoding model for a highly-reliable DNA data storage

A Rasool, J Hong, Q Jiang, H Chen, Q Qu - Computers in Biology and …, 2023 - Elsevier
DNA data storage is a promising technology that utilizes computer simulation, and synthetic
biology, offering high-density and reliable digital information storage. It is challenging to …

GCNSA: DNA storage encoding with a graph convolutional network and self-attention

B Cao, B Wang, Q Zhang - Iscience, 2023 - cell.com
DNA Encoding, as a key step in DNA storage, plays an important role in reading and writing
accuracy and the storage error rate. However, currently, the encoding efficiency is not high …

A mixed reality-based navigation method for dental implant navigation method: a pilot study

L Liu, X Wang, M Guan, Y Fan, Z Yang, D Li… - Computers in Biology …, 2023 - Elsevier
This in vitro study aimed to put forward the development and investigation of a novel Mixed
Reality (MR)-based dental implant navigation method and evaluate implant accuracy. Data …

DNMG: Deep molecular generative model by fusion of 3D information for de novo drug design

T Song, Y Ren, S Wang, P Han, L Wang, X Li… - Methods, 2023 - Elsevier
Deep learning is improving and changing the process of de novo molecular design at a
rapid pace. In recent years, great progress has been made in drug discovery and …

DUHI: dynamically updated hash index clustering method for DNA storage

P Wang, B Cao, T Ma, B Wang, Q Zhang… - Computers in Biology and …, 2023 - Elsevier
The exponential growth of global data leads to the problem of insufficient data storage
capacity. DNA storage can be an ideal storage method due to its high storage density and …

Construction of DNA-based molecular circuits using normally open and normally closed switches driven by lambda exonuclease

X Liu, X Zhang, Y Yao, P Shi, C Zeng, Q Zhang - Nanoscale, 2023 - pubs.rsc.org
Building synthetic molecular circuits is an important way to realize ion detection, information
processing, and molecular computing. However, it is still challenging to implement the NOT …

High net information density DNA data storage by the MOPE encoding algorithm

Y Zheng, B Cao, J Wu, B Wang… - IEEE/ACM Transactions …, 2023 - ieeexplore.ieee.org
DNA has recently been recognized as an attractive storage medium due to its high reliability,
capacity, and durability. However, encoding algorithms that simply map binary data to DNA …

[HTML][HTML] Weakly mutually uncorrelated codes with maximum run length constraint for DNA storage

X Lu, S Kim - Computers in Biology and Medicine, 2023 - Elsevier
DNA storage systems have begun to attract considerable attention as next-generation
storage technologies due to their high densities and longevity. However, efficient primer …

Reconfigurable DNA triplex structure for pH responsive logic gates

M Qi, P Shi, X Zhang, S Cui, Y Liu, S Zhou, Q Zhang - RSC advances, 2023 - pubs.rsc.org
The DNA triplex is a special DNA structure often used as a logic gate substrate due to its
high stability, programmability, and pH responsiveness. However, multiple triplex structures …