The innervation of bone has been described for centuries, and our understanding of its
function has rapidly evolved over the past several decades to encompass roles of subtype …

Hu proteins are RNA-binding proteins involved in diverse biological processes. The
neuronal members of the Hu family, HuB, HuC, and HuD play important roles in neuronal …

A general strategy for selecting insertion mutations in mice has been devised. Constructs
lacking a promoter and including a beta-galactosidase gene, or a reporter gene encoding a …

Calcitonin precursors (CTpr), including procalcitonin, are important markers and also
potentially harmful mediators in response to microbial infections. The source and function of …

Signalling through dopamine D2 receptors governs physiological functions related to
locomotion, hormone production and drug abuse,,,,,,. D2 receptors are also known targets of …

The ability to introduce foreign genes into the germ line and the successful expression of the
inserted gene in the organism have allowed the genetic manipulation of animals on an …

Many genes have been described and characterized which result in alternative
polyadenylation site use at the 3′-end of their mRNAs based on the cellular environment …

Paraneoplastic opsoclonus-ataxia, a disorder of motor control, develops in breast or lung
cancer patients who harbor an antibody (Ri) that recognizes their tumors and a nuclear …

The mouse quaking gene, essential for nervous system myelination and survival of the early
embryo has been positionally cloned. Its sequence implies that the locus encodes a …

A masterful guide to human development that redefines the nature versus nurture debate A
much-needed antidote to genetic determinism, The Dependent Gene reveals how all traits …