In addition to determining biological sex, sex hormones are known to influence health and
disease via regulation of immune cell activities and modulation of target-organ susceptibility …

Androgens in women, as well as in men, are intrinsic to maintenance of (i) reproductive
competency,(ii) cardiac health,(iii) appropriate bone remodeling and mass retention,(iii) …

Importance Preclinical and epidemiological studies indicate a potential chemopreventive
role of statins in epithelial ovarian cancer risk. Objective To evaluate the association of …

Sex is known to be an important factor in the incidence, progression, and outcome of cancer.
A better understanding of the underlying mechanisms could help improve cancer prevention …

Background Various risk factors have been associated with epithelial ovarian cancer risk in
observational epidemiological studies. However, the causal nature of the risk factors …

There is evidence that gender-affirming hormone treatment (GAHT) for transgender
individuals modulates their risk for specific malignancies including breast and prostate …

Repeated exposure to the acute proinflammatory environment that follows ovulation at the
ovarian surface and distal fallopian tube over a woman's reproductive years may increase …

Purpose: Ovarian cancer is a heterogeneous disease that can be divided into multiple
subtypes with variable etiology, pathogenesis, and prognosis. We analyzed DNA …

STUDY QUESTION How does exposure to a testosterone rich environment affect the
function and gene expression of human fallopian tube epithelium (hFTE)? SUMMARY …

Background Testosterone plays a key role in women, but the associations of serum
testosterone level with gynecological disorders risk are inconclusive in observational …