Cerebral radiation necrosis: a review of the pathobiology, diagnosis and management considerations

G Rahmathulla, NF Marko, RJ Weil - Journal of Clinical Neuroscience, 2013 - Elsevier
Radiation therapy forms one of the building blocks of the multi-disciplinary management of
patients with brain tumors. Improved survival following radiation therapy may come with a …

The molecular epidemiology of lung cancer

AG Schwartz, GM Prysak, CH Bock, ML Cote - Carcinogenesis, 2007 - academic.oup.com
Lung cancer is the leading cause of cancer mortality worldwide. There have been only slight
improvements in early diagnosis and survival, reflecting limited advances in screening and …

Single nucleotide polymorphisms of DNA repair genes as predictors of radioresponse

MB Parliament, D Murray - Seminars in radiation oncology, 2010 - Elsevier
Radiation therapy is a key modality in the treatment of cancer. Substantial progress has
been made in unraveling the molecular events which underpin the responses of malignant …

Association of Single Nucleotide Polymorphisms in SOD2, XRCC1 and XRCC3 with Susceptibility for the Development of Adverse Effects Resulting from …

RJ Burri, RG Stock, JA Cesaretti… - Radiation …, 2008 - meridian.allenpress.com
Abstract Burri, RJ, Stock, RG, Cesaretti, JA, Atencio, DP, Peters, S., Peters, CA, Fan, G.,
Stone, NN, Ostrer, H. and Rosenstein, BS Association of Single Nucleotide Polymorphisms …

Genetic polymorphisms and head and neck cancer outcomes: a review

J Hopkins, DW Cescon, D Tse, P Bradbury, W Xu… - … Biomarkers & Prevention, 2008 - AACR
Head and neck cancer (HNC) patients have variable prognoses even within the same
clinical stage and while receiving similar treatments. The number of studies of genetic …

Genetic variation in the DNA repair genes is predictive of outcome in lung cancer

A Matakidou, R El Galta, EL Webb… - Human molecular …, 2007 - academic.oup.com
To assess whether DNA repair gene variants influence the clinical behaviour of lung cancer
we examined the impact of a comprehensive panel of 109 non-synonymous single …

High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma

MK Ang, MR Patel, XY Yin, S Sundaram, K Fritchie… - Clinical Cancer …, 2011 - AACR
Purpose: We evaluated X-ray repair complementing defective repair in Chinese hamster
cells 1 (XRCC1) protein in head and neck squamous cell carcinoma (HNSCC) patients in …

Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy

E Cecchin, M Agostini, S Pucciarelli… - The …, 2011 - nature.com
The aim of the study was the identification of a pharmacogenetic profile predictive of the
tumor regression grade (TRG), considered as tumor response parameter, after neo-adjuvant …

Evaluation of XRCC1 gene polymorphism as a biomarker in head and neck cancer patients undergoing chemoradiation therapy

SS Nanda, AK Gandhi, M Rastogi, R Khurana… - International Journal of …, 2018 - Elsevier
Purpose We evaluated the correlation of the x-ray repair cross complementing gene 1
(XRCC1) Arg194Trp polymorphism with clinical outcomes in head and neck squamous cell …

ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer

A Vaezi, CH Feldman… - … and personalized medicine, 2011 - Taylor & Francis
Advanced stage non-small cell lung cancer and head and neck squamous cell carcinoma
are both treated with DNA damaging agents including platinum-based compounds and …