The prominent role of CD44 in tumor cell signaling together with its establishment as a
cancer stem cell (CSC) marker for various tumor entities imply a key role for CD44 in CSC …

The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …

The adult central nervous system (CNS) contains resident stem cells within specific niches
that maintain a self-renewal and proliferative capacity to generate new neurons, astrocytes …

Tissue regeneration is an active multiplex process involving the dynamic inflammatory
microenvironment. Under a normal physiological framework, inflammation is necessary for …

Abstract spinal cord injury (SCI) is a traumatic damage that can causes a loss of neurons
around the lesion site and resulting in locomotor and sensory deficits. Currently, there is …

Recent evidence based studies have proposed hyaluronic acid (HA) as an emerging
biopolymer for various tissue engineering application. Meanwhile, stem cells (SCs) have …

The identity of cancer stem cells (CSCs) remains an enigma, with the question outstanding
of whether CSCs are fixed entities or plastic cell states in response to microenvironmental …

Myelin is an essential structure that protects axons, provides metabolic support to neurons
and allows fast nerve transmission. Several neurological diseases, such as multiple …

Hyaluronic acid (HA) plays a vital role in the extracellular matrix of neural tissues. Originally
thought to hydrate tissues and provide mechanical support, it is now clear that HA is also a …