Same substrate, many reactions: oxygen activation in flavoenzymes
Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Discovery and characterization of a 5-hydroxymethylfurfural oxidase from Methylovorus sp. strain MP688
WP Dijkman, MW Fraaije - Applied and environmental …, 2014 - Am Soc Microbiol
In the search for useful and renewable chemical building blocks, 5-hydroxymethylfurfural
(HMF) has emerged as a very promising candidate, as it can be prepared from sugars. HMF …
(HMF) has emerged as a very promising candidate, as it can be prepared from sugars. HMF …
Structure-based enzyme tailoring of 5-hydroxymethylfurfural oxidase
5-Hydroxymethylfurfural oxidase (HMFO) is a flavin-dependent enzyme that catalyzes the
oxidation of many aldehydes, primary alcohols, and thiols. The three-step conversion of 5 …
oxidation of many aldehydes, primary alcohols, and thiols. The three-step conversion of 5 …
Choline oxidases
G Gadda - The Enzymes, 2020 - Elsevier
Choline oxidase catalyzes the four-electron, two-step, flavin-mediated oxidation of choline to
glycine betaine. The enzyme is important both for medical and biotechnological reasons …
glycine betaine. The enzyme is important both for medical and biotechnological reasons …
A High‐Performance Base‐Metal Approach for the Oxidative Esterification of 5‐Hydroxymethylfurfural
Y Sun, H Ma, X Jia, J Ma, Y Luo, J Gao, J Xu - ChemCatChem, 2016 - Wiley Online Library
Exploring high‐performance base‐metal approaches for the sustainable production of
chemicals from biomass is presently attracting immense interest and is truly important to …
chemicals from biomass is presently attracting immense interest and is truly important to …
Crystal Structure of Alcohol Oxidase from Pichia pastoris
C Koch, P Neumann, O Valerius, I Feussner, R Ficner - PLoS One, 2016 - journals.plos.org
FAD-dependent alcohol oxidases (AOX) are key enzymes of methylotrophic organisms that
can utilize lower primary alcohols as sole source of carbon and energy. Here we report the …
can utilize lower primary alcohols as sole source of carbon and energy. Here we report the …
Metal-Triggered FAD Reduction in d-2-Hydroxyglutarate Dehydrogenase from Pseudomonas aeruginosa PAO1
Alcohol oxidation is an indispensable chemical reaction in biological systems. This process,
biologically catalyzed by alcohol dehydrogenases (ADHs) and alcohol oxidases (AOXs) …
biologically catalyzed by alcohol dehydrogenases (ADHs) and alcohol oxidases (AOXs) …
Anaerobic methods for the transient-state study of flavoproteins: the use of specialized glassware to define the concentration of dioxygen
GR Moran - Methods in enzymology, 2019 - Elsevier
The methods described here concern the use specialized glassware to achieve accurate
sub-micromolar to low-millimolar dioxygen concentrations specifically for the study of …
sub-micromolar to low-millimolar dioxygen concentrations specifically for the study of …
The Pseudomonas aeruginosa PAO1 metallo flavoprotein D-2-hydroxyglutarate dehydrogenase requires Zn2+ for substrate orientation and activation
Pseudomonas aeruginosa PAO1 d-2-hydroxyglutarate (D2HG) dehydrogenase
(PaD2HGDH) oxidizes D2HG to 2-ketoglutarate during the vital l-serine biosynthesis and is …
(PaD2HGDH) oxidizes D2HG to 2-ketoglutarate during the vital l-serine biosynthesis and is …
[HTML][HTML] Enantioselective oxidation of secondary alcohols by the flavoprotein alcohol oxidase from Phanerochaete chrysosporium
G Tjallinks, C Martin, MW Fraaije - Archives of Biochemistry and Biophysics, 2021 - Elsevier
The enantioselective oxidation of secondary alcohols represents a valuable approach for
the synthesis of optically pure compounds. Flavoprotein oxidases can catalyse such …
the synthesis of optically pure compounds. Flavoprotein oxidases can catalyse such …