The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Design and synthesis of SERS materials for in vivo molecular imaging and biosensing

Q Li, H Huo, Y Wu, L Chen, L Su, X Zhang… - Advanced …, 2023 - Wiley Online Library
Surface‐enhanced Raman scattering (SERS) is a feasible and ultra‐sensitive method for
biomedical imaging and disease diagnosis. SERS is widely applied to in vivo imaging due …

Near-infrared II plasmonic porous cubic nanoshells for in vivo noninvasive SERS visualization of sub-millimeter microtumors

L Li, R Jiang, B Shan, Y Lu, C Zheng, M Li - Nature Communications, 2022 - nature.com
In vivo surface-enhanced Raman scattering (SERS) imaging allows non-invasive
visualization of tumors for intraoperative guidance and clinical diagnostics. However, the in …

Expanding the multiplexing capabilities of raman imaging to reveal highly specific molecular expression and enable spatial profiling

OE Eremina, AT Czaja, A Fernando, A Aron… - ACS …, 2022 - ACS Publications
Profiling the heterogeneous landscape of cell types and biomolecules is rapidly being
adopted to address current imperative research questions. Precision medicine seeks …

Absolute quantification of serum exosomes in patients with an sers-lateral flow strip biosensor for noninvasive clinical cancer diagnosis

X Su, Y Xie, X Liu, M Chen, C Zheng… - ACS Applied Materials …, 2023 - ACS Publications
Exosomes (exos) widely existing in body fluids show great potential for noninvasive cancer
diagnosis. Quantitative analysis of exos is traditionally performed by targeting specific …

Highly Excretable Gold Supraclusters for Translatable In Vivo Raman Imaging of Tumors

JH Yu, MS Jeong, EO Cruz, IS Alam, SK Tumbale… - Acs Nano, 2023 - ACS Publications
Raman spectroscopy provides excellent specificity for in vivo preclinical imaging through a
readout of fingerprint-like spectra. To achieve sufficient sensitivity for in vivo Raman imaging …

Laser transparent multiplexed SERS microneedles for in situ and real-time detection of inflammation

C Peng, L Jin, F Wang, H Yang, H He - Biosensors and Bioelectronics, 2023 - Elsevier
It is a significant challenge to perform painless invasive detection of inflammation
progression in relation to the evolution of pH, redox potential, and reactive oxygen species …

Molecular jackhammers eradicate cancer cells by vibronic-driven action

C Ayala-Orozco, D Galvez-Aranda, A Corona… - Nature Chemistry, 2024 - nature.com
Through the actuation of vibronic modes in cell-membrane-associated aminocyanines,
using near-infrared light, a distinct type of molecular mechanical action can be exploited to …

Four-Color SERS Monitoring of Size-dependent Nanoparticle Delivery in the Same Tumor

C Liu, J Dong, Z Zhang, K Fu, D Wang, X Mi… - Analytical …, 2023 - ACS Publications
The physicochemical properties of nanoparticles (NPs) significantly influence their
deposition at the disease site, ultimately impacting the overall therapeutic efficacy; however …

Potential Application Prospects of Biomolecule-Modified Two-Dimensional Chiral Nanomaterials in Biomedicine

LX Zhao, LL Chen, D Cheng, TY Wu… - ACS Biomaterials …, 2024 - ACS Publications
Chirality, one of the most fundamental properties of natural molecules, plays a significant
role in biochemical reactions. Nanomaterials with chiral characteristics have superior …