Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions

ME Griffin, S Klupt, J Espinosa, HC Hang - Cell chemical biology, 2023 - cell.com
The bacterial cell wall is composed of a highly crosslinked matrix of glycopeptide polymers
known as peptidoglycan that dictates bacterial cell morphology and protects against …

Lateral gene transfer mechanisms and pan-genomes in eukaryotes

SJ Sibbald, L Eme, JM Archibald, AJ Roger - Trends in parasitology, 2020 - cell.com
Lateral gene transfer (LGT) is well known as an important driver of genome evolution in
bacteria and archaea, but its importance in eukaryote evolution has yet to be fully …

Lactobacillus gasseri and Gardnerella vaginalis produce extracellular vesicles that contribute to the function of the vaginal microbiome and modulate host …

A Artuyants, J Hong, P Dauros‐Singorenko… - Molecular …, 2024 - Wiley Online Library
Trichomonas vaginalis is an extracellular protozoan parasite of the human urogenital tract,
responsible for a prevalent sexually transmitted infection. Trichomoniasis is accompanied by …

Identification and classification of papain-like cysteine proteinases

F Ozhelvaci, K Steczkiewicz - Journal of Biological Chemistry, 2023 - ASBMB
Papain-like cysteine peptidases form a big and highly diverse superfamily of proteins
involved in many important biological functions, such as protein turnover, deubiquitination …

Vaginal Microbiota of the Sexually Transmitted Infections Caused by Chlamydia trachomatis and Trichomonas vaginalis in Women with Vaginitis in Taiwan

SF Chiu, PJ Huang, WH Cheng, CY Huang, LJ Chu… - Microorganisms, 2021 - mdpi.com
The three most common sexually transmitted infections (STIs) are Chlamydia trachomatis
(CT), Neisseria gonorrhoeae (GC) and Trichomonas vaginalis (TV). The prevalence of these …

Proteomic analysis of Trichomonas vaginalis phagolysosome, lysosomal targeting, and unconventional secretion of cysteine peptidases

N Zimmann, P Rada, V Žárský, T Smutná… - Molecular & Cellular …, 2022 - ASBMB
The lysosome represents a central degradative compartment of eukaryote cells, yet little is
known about the biogenesis and function of this organelle in parasitic protists. Whereas the …

An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular …

J Reuter, C Otten, N Jacquier, J Lee… - PLoS …, 2023 - journals.plos.org
The obligate intracellular Chlamydiaceae do not need to resist osmotic challenges and thus
lost their cell wall in the course of evolution. Nevertheless, these pathogens maintain a …

Interplay between Histomonas meleagridis and bacteria: mutualistic or predator–prey?

I Bilic, M Hess - Trends in parasitology, 2020 - cell.com
Histomonas meleagridis is an extracellular protozoan parasite and the aetiological agent of
histomonosis, an important poultry disease whose impact is greatly accentuated by …

[HTML][HTML] Recent advances in the molecular biology of the protist parasite Trichomonas vaginalis

D Leitsch - Faculty Reviews, 2021 - ncbi.nlm.nih.gov
Trichomonas vaginalis is an anaerobic/microaerophilic protist parasite which causes
trichomoniasis, one of the most prevalent sexually transmitted diseases worldwide. T …

Tandem mass tag-based quantitative proteomics analyses of a chicken-original virulent and its attenuated Histomonas meleagridis strain in China

QG Chen, YM Zhang, C Chen, S Wang, ZF Li… - Frontiers in Veterinary …, 2023 - frontiersin.org
Introduction Histomonas meleagridis can cause histomonosis in poultry. Due to the
prohibition of effective drugs, the prevention and treatment of the disease requires new …