Neonatal multimorbidity and the phenotype of premature aging in preterm infants

JS Litt, MB Belfort, TM Everson, S Haneuse… - Pediatric …, 2024 - nature.com
Multimorbidity is the co-occurrence of multiple chronic health problems, associated with
aging, frailty, and poor functioning. Children born preterm experience more multimorbid …

Cross-sectional association between plasma biomarkers and multimorbidity patterns in older adults

A Vázquez-Fernández, A Lana… - The Journals of …, 2024 - academic.oup.com
Multimorbidity is the simultaneous presence of 2 or more chronic conditions. Metabolomics
could identify biomarkers potentially related to multimorbidity. We aimed to identify groups of …

The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors

Y van Holstein, SP Mooijaart, M van Oevelen… - GeroScience, 2024 - Springer
Prognostic information is needed to balance benefits and risks of cancer treatment in older
patients. Metabolomics-based scores were previously developed to predict 5-and 10-year …

Metabolite and protein associations with general health in the population-based CHRIS study

E Hantikainen, CX Weichenberger, N Dordevic… - Scientific Reports, 2024 - nature.com
Identifying biomarkers able to discriminate individuals on different health trajectories is
crucial to understand the molecular basis of age-related morbidity. We investigated multi …

Prospective association between plasma concentrations of fatty acids and other lipids, and multimorbidity in older adults

FF Caballero, A Lana, EA Struijk… - The Journals of …, 2023 - academic.oup.com
Biological mechanisms that lead to multimorbidity are mostly unknown, and metabolomic
profiles are promising to explain different pathways in the aging process. The aim of this …

Novel binuclear copper (II) complexes with sulfanylpyrazole ligands: synthesis, crystal structure, fungicidal, cytostatic, and cytotoxic activity

VR Akhmetova, NS Akhmadiev, AT Gubaidullin… - Metallomics, 2024 - academic.oup.com
New binuclear copper (II)[Cu (II)] tetraligand complexes (six examples) with sulfanylpyrazole
ligands were synthesized. Electron spin resonance (ESR) studies have shown that in …

Identifying Metabolomic and Proteomic Biomarkers for Age-Related Morbidity in a Population-Based Cohort-the Cooperative Health Research in South Tyrol (CHRIS) …

E Hantikainen, CX Weichenberger, N Dordevic… - medRxiv, 2024 - medrxiv.org
Identifying biomarkers able to discriminate individuals on different health trajectories is
crucial to understand the molecular basis of age-related morbidity. We investigated multi …

Molecular bases of comorbidities: present and future perspectives

J Sánchez-Valle, A Valencia - Trends in Genetics, 2023 - cell.com
Co-occurrence of diseases decreases patient quality of life, complicates treatment choices,
and increases mortality. Analyses of electronic health records present a complex scenario of …