Chronic hepatitis B virus infection
Chronic hepatitis B virus infection is a global public health threat that causes considerable
liver-related morbidity and mortality. It is acquired at birth or later via person-to-person …
liver-related morbidity and mortality. It is acquired at birth or later via person-to-person …
The evolution and clinical impact of hepatitis B virus genome diversity
The global burden of hepatitis B virus (HBV) is enormous, with 257 million persons
chronically infected, resulting in more than 880,000 deaths per year worldwide. HBV exists …
chronically infected, resulting in more than 880,000 deaths per year worldwide. HBV exists …
Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update
YF Liaw, JH Kao, T Piratvisuth, HLY Chan… - Hepatology …, 2012 - Springer
Large volume of new data on the natural history and treatment of chronic hepatitis B virus
(HBV) infection have become available since 2008. These include further studies in …
(HBV) infection have become available since 2008. These include further studies in …
[HTML][HTML] Guideline of prevention and treatment for chronic hepatitis B (2015 update)
J Hou, G Wang, F Wang, J Cheng, H Ren… - Journal of clinical and …, 2017 - ncbi.nlm.nih.gov
The Chinese Society of Hepatology, Chinese Medical Association (CMA) and the Society of
Infectious Diseases, CMA organized relevant native experts to establish this Guideline of …
Infectious Diseases, CMA organized relevant native experts to establish this Guideline of …
Evolutionary analysis of the dynamics of viral infectious disease
Many organisms that cause infectious diseases, particularly RNA viruses, mutate so rapidly
that their evolutionary and ecological behaviours are inextricably linked. Consequently …
that their evolutionary and ecological behaviours are inextricably linked. Consequently …
[HTML][HTML] Control of cccDNA function in hepatitis B virus infection
M Levrero, T Pollicino, J Petersen, L Belloni… - Journal of …, 2009 - Elsevier
The template of hepatitis B virus (HBV) transcription, the covalently closed circular DNA
(cccDNA), plays a key role in the life-cycle of the virus and permits the persistence of …
(cccDNA), plays a key role in the life-cycle of the virus and permits the persistence of …
Serum hepatitis B surface antigen and hepatitis B e antigen titers: disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers
AJV Thompson, T Nguyen, D Iser, A Ayres… - …, 2010 - Wiley Online Library
Although threshold levels for hepatitis B surface antigen (HBsAg) and hepatitis B e antigen
(HBeAg) titers have recently been proposed to guide therapy for chronic hepatitis B (CHB) …
(HBeAg) titers have recently been proposed to guide therapy for chronic hepatitis B (CHB) …
New insight in the pathobiology of hepatitis B virus infection
M Dandri, S Locarnini - Gut, 2012 - gut.bmj.com
Chronic hepatitis B virus (HBV) infection remains a major health burden and the main risk
factor for the development of hepatocellular carcinoma worldwide. However, HBV is not …
factor for the development of hepatocellular carcinoma worldwide. However, HBV is not …
[HTML][HTML] Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance
CMN Croagh, PV Desmond, SJ Bell - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Abstract The Hepatitis B Virus (HBV) has a worldwide distribution and is endemic in many
populations. It is constantly evolving and 10 genotypic strains have been identified with …
populations. It is constantly evolving and 10 genotypic strains have been identified with …
Viral hepatitis B: clinical and epidemiological characteristics
GS Burns, AJ Thompson - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
It is now 50 years since the discovery of the hepatitis B virus (HBV), and, despite the
availability of a prophylactic vaccine for more than 20 years, HBV infection remains a …
availability of a prophylactic vaccine for more than 20 years, HBV infection remains a …