The “serrated neoplastic pathway” describes the progression of serrated polyps, including
sessile serrated adenomas and traditional serrated adenomas, to colorectal cancer. The …

Purpose A number of studies have investigated the relationship between microsatellite
instability (MSI) and colorectal cancer (CRC) prognosis. Although many have reported a …

Background Colon cancers with high-frequency microsatellite instability have clinical and
pathological features that distinguish them from microsatellite-stable tumors. We …

Purpose To update the recommendations for the use of tumor marker tests in the prevention,
screening, treatment, and surveillance of gastrointestinal cancers. Methods For the 2006 …

Colorectal cancers with microsatellite instability (MSI) represent 15% of all colorectal
cancers, including Lynch syndrome as the most frequent hereditary form of this disease …

2.1 Geltungsbereich und Zweck 2.1. 1. Zielsetzung und Fragestellung Das Kolorektale
Karzinom (KRK) ist mit etwa 64 000 Neuerkrankungen und ca. 26 000 Todesfällen pro Jahr …

BACKGROUND AND METHODS: We have reviewed and pooled data from published
studies to evaluate the relationship between microsatellite instability (MSI) and colorectal …

BACKGROUND Cells with deficient DNA mismatch repair develop microsatellite instability.
Extensive microsatellite instability (MSI‐high) is characteristic of colorectal carcinomas in …

An understanding of the mechanisms that explain the initiation and early evolution of
colorectal cancer should facilitate the development of new approaches to effective …

Purpose: Many studies have evaluated the role of high levels of microsatellite instability
(MSI) as a prognostic marker and predictor of the response to chemotherapy in colorectal …