Management of endocrine disease: Cushing's syndrome due to ectopic ACTH secretion: an expert operational opinion

J Young, M Haissaguerre, O Viera-Pinto… - European journal of …, 2020 - academic.oup.com
Ectopic ACTH syndrome (EAS) is rare but is frequently a severe condition because of the
intensity of the hypercortisolism that may be dissociated from the tumoral condition. EAS …

The immune system in Cushing's syndrome

V Hasenmajer, E Sbardella, F Sciarra… - Trends in endocrinology …, 2020 - cell.com
Cushing's syndrome (CS), or chronic hypercortisolism, induces a variety of alterations in the
immune system, often leading to severe clinical complications such as sepsis and …

Cushing syndrome: a review

M Reincke, M Fleseriu - Jama, 2023 - jamanetwork.com
Importance Cushing syndrome is defined as a prolonged increase in plasma cortisol levels
that is not due to a physiological etiology. Although the most frequent cause of Cushing …

Cushing's syndrome: Overview of clinical presentation, diagnostic tools and complications

M Barbot, M Zilio, C Scaroni - … practice & research Clinical endocrinology & …, 2020 - Elsevier
Cushing's syndrome (CS) is a severe condition that results from chronic exposure to
elevated circulating cortisol levels; it is a rare but potentially life-threating condition …

Long‐term morbidity and mortality in patients with Cushing's syndrome

LT Braun, F Vogel, M Reincke - Journal of neuroendocrinology, 2022 - Wiley Online Library
Increased multisystem morbidity and mortality in patients with Cushing's syndrome comprise
clinical problems and challenges, both at the time of diagnosis and in remission. Relevant …

Clinical presentation and etiology of Cushing's syndrome: Data from ERCUSYN

E Valassi - Journal of Neuroendocrinology, 2022 - Wiley Online Library
This review presents the data on clinical presentation at diagnosis in 1564 patients included
in the European Registry on Cushing's syndrome (ERCUSYN), of whom 1045 (67%) had …

The effect of endogenous cushing syndrome on all-cause and cause-specific mortality

P Limumpornpetch, AW Morgan… - The Journal of …, 2022 - academic.oup.com
Objective We aimed to perform a systematic review and meta-analysis of all-cause and
cause-specific mortality of patients with benign endogenous Cushing syndrome (CS) …

[HTML][HTML] Cardiovascular complications of Cushings Syndrome: impact on morbidity and mortality

RN Clayton - Journal of Neuroendocrinology, 2022 - ncbi.nlm.nih.gov
Patients with Cushing's syndrome have increased morbidity and mortality from
cardiovascular causes, most commonly myocardial infarction and stroke, but also …

Cushing's syndrome

M Gadelha, F Gatto, LE Wildemberg, M Fleseriu - The Lancet, 2023 - thelancet.com
Endogenous Cushing's syndrome results from excess glucocorticoid secretion, which leads
to a myriad of clinical manifestations, comorbidities, and increased mortality despite …

An individualized approach to the management of Cushing disease

M Fleseriu, EV Varlamov, JM Hinojosa-Amaya… - Nature Reviews …, 2023 - nature.com
Cushing disease caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary
corticotroph adenoma leads to hypercortisolaemia with high mortality due to metabolic …