Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …

Enormous advances in our understanding of the chemistry underlying life processes have
identified new targets for therapeutic agents. The discovery of effective therapeutics to …

Proteomics can be viewed as an experimental approach to explain the information
contained in genomic sequences in terms of the structure, function, and control of biological …

The analysis of peptides and proteins as well as the grander scope of proteomics (large
scale study of proteins) has been advanced by the development of a versatile array of ion …

The detection, correlation, and comparison of peptide and product ions from a data
independent LC‐MS acquisition strategy with data dependent LC‐MS/MS is described. The …

One of the most important early developments in the field of proteomics was the advent of
automated data acquisition routines that allowed high‐throughput unattended data …

This review provides a broad overview of recent Fourier transform ion cyclotron resonance
(FTICR) applications and technological developments relevant to the field of proteomics …

Over the past decade, the data-independent acquisition mode has gained popularity for
broad coverage of complex proteomes by LC-MS/MS and quantification of low-abundance …

Data-dependent precursor ion selection is widely used in shotgun proteomics to profile the
protein components of complex samples. Although very popular, this bottom-up method …

We describe high-efficiency (peak capacities of∼ 103) nanoscale (using column inner
diameters down to 15 μ m) liquid chromatography (nanoLC)/low flow rate electrospray …