Spinal cord stimulation for spasticity: historical approaches, current status, and future directions
Introduction Millions of people worldwide suffer with spasticity related to irreversible damage
to the brain or spinal cord. Typical antecedent events include stroke, traumatic brain injury …
to the brain or spinal cord. Typical antecedent events include stroke, traumatic brain injury …
Spinal dura mater: biophysical characteristics relevant to medical device development
Understanding the relevant biophysical properties of the spinal dura mater is essential to the
design of medical devices that will directly interact with this membrane or influence the …
design of medical devices that will directly interact with this membrane or influence the …
Kinematic analysis of the gait of adult sheep during treadmill locomotion: parameter values, allowable total error, and potential for use in evaluating spinal cord injury
S Safayi, ND Jeffery, SK Shivapour… - Journal of the …, 2015 - Elsevier
We are developing a novel intradural spinal cord (SC) stimulator designed to improve the
treatment of intractable pain and the sequelae of SC injury. In-vivo ovine models of …
treatment of intractable pain and the sequelae of SC injury. In-vivo ovine models of …
An ovine model of spinal cord injury
S Wilson, KO Abode-Iyamah, JW Miller… - The journal of spinal …, 2017 - Taylor & Francis
Objective: To develop a large animal model of spinal cord injury (SCI), for use in
translational studies of spinal cord stimulation (SCS) in the treatment of spasticity. We seek …
translational studies of spinal cord stimulation (SCS) in the treatment of spasticity. We seek …
The hemisection approach in large animal models of spinal cord injury: overview of methods and applications
Introduction: Translating basic science research into a safe and effective therapy for spinal
cord injury (SCI) requires suitable large animal models for testing both implantable devices …
cord injury (SCI) requires suitable large animal models for testing both implantable devices …
[HTML][HTML] Intradural spinal cord stimulation: performance modeling of a new modality
Introduction: Intradural spinal cord stimulation (SCS) may offer significant therapeutic
benefits for those with intractable axial and extremity pain, visceral pain, spasticity …
benefits for those with intractable axial and extremity pain, visceral pain, spasticity …
Ovine model of neuropathic pain for assessing mechanisms of spinal cord stimulation therapy via dorsal horn recordings, von Frey filaments, and gait analysis
CG Reddy, JW Miller, KO Abode-Iyamah… - Journal of pain …, 2018 - Taylor & Francis
Background It is becoming increasingly important to understand the mechanisms of spinal
cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise …
cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise …
Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain
S Safayi, JW Miller, S Wilson… - Journal of medical …, 2016 - Taylor & Francis
Our laboratories are developing treadmill-based gait analysis employing sheep to
investigate potential efficacy of intra-dural spinal cord stimulation in the treatment of spinal …
investigate potential efficacy of intra-dural spinal cord stimulation in the treatment of spinal …
Revisiting intradural spinal cord stimulation: an introduction to a novel intradural spinal cord stimulation device
BD Dalm, SV Viljoen, NS Dahdaleh… - Innovative …, 2014 - degruyter.com
Background: Spinal cord stimulation has been in use for decades and is growing as a
therapeutic treatment option. A significant problem arising from the epidural location of the …
therapeutic treatment option. A significant problem arising from the epidural location of the …
Contemporary approaches to preventing and treating infections of novel intrathecal neurostimulation devices
Introduction Contemporary approaches to surgical site infections have evolved significantly
over the last several decades in response to the economic pressures of soaring health care …
over the last several decades in response to the economic pressures of soaring health care …