Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

The availability of plastic microspheres labeled with different-emitting isotopes has allowed
the quantification of blood flow in different organs, including the heart (1). In the past 3 …

Reactive oxygen species (ROS), such as the superoxide anion or hydrogen peroxide, have
been established over decades of research as, on the one hand, important and versatile …

The endothelium maintains vascular homeostasis through the release of active vasodilators.
Although nitric oxide (NO) is recognized as the primary factor at level of conduit arteries …

Background—Coronary endothelial function and vasomotion are impaired in smokers
without coronary disease, and this is thought to be due to increased oxidative stress …

Nitric oxide (NO) produced by the endothelium diffuses both into the lumen and to the
smooth muscle cells according to the concentration gradient in each direction. The …

Activation of cells by receptor-and nonreceptor-mediated stimuli not only requires a change
in the activity of signaling proteins but also requires a reorganization of the topology of the …

Arginase shares a common substrate, L‐arginine, with nitric oxide (NO) synthase (NOS). It is
thought that arginase, if it is expressed in the endothelium, might play a pivotal role in the …

OBJECTIVES The present study evaluates the impact of total cholesterol (TC) and its
subfractions on coronary flow reserve (CFR), an index of the integrated function of the …

BACKGROUND AND OBJECTIVE: Elevated C-reactive protein (CRP) levels are associated
with increased cardiovascular events and endothelial dysfunction. We have previously …