Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …

Novel quinoline derivatives carrying nitrones and oxime as nitric oxide donors were
prepared and characterized using different spectroscopic techniques. Nitrones can release …

Fungal infections have emerged as a current serious global public health problem. The main
problem involving these infections is the expansion of multidrug resistance. Therefore, the …

In this work, readily achievable synthetic pathways were utilized for construction of a library
of N/S analogues based on the pyrazolopyrimidine scaffold with terminal alkyl or aryl …

Cancer is a term used for diseases in which some of the body's cells begin to divide without
stopping and spread into surrounding tissues. Most cancers form a tumor, but some, like …

Quinoline heterocycle is a useful scaffold to develop bioactive molecules used as
anticancer, antimalaria, and antimicrobials. Inspired by their numerous biological activities …

We report the synthesis of some novel β-lactam hybrids of 2-mercaptobenzothiazole and
benzoquinoline. These compounds were synthesized by a [2+ 2]-cycloaddition reaction of …

Atualmente, as infecções fúngicas sistêmicas são uma das maiores problemáticas na saúde
pública, uma vez que possuem altas taxas de mortalidade e uma terapia limitada …

Quinoline heterocycle is a useful scaffold to develop bioactive molecules used as
anticancer, antimalaria, and antimicrobials. Inspired by their numerous biological activities …

Benzoxaborole structure contains a phenyl ring fused with a heterocyclic oxaborole ring
moiety. Benzoxaboroles are considerably more stable and exhibit high hydrolytic resistance …