The influence of gut dysbiosis in the pathogenesis and management of ischemic stroke

SB Chidambaram, AG Rathipriya, AM Mahalakshmi… - Cells, 2022 - mdpi.com
Recent research on the gut microbiome has revealed the influence of gut microbiota (GM)
on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …

The oral microbiome in the pathophysiology of cardiovascular disease

A Tonelli, EN Lumngwena, NAB Ntusi - Nature Reviews Cardiology, 2023 - nature.com
Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

The gut microbiome and the brain

L Galland - Journal of medicinal food, 2014 - liebertpub.com
The human gut microbiome impacts human brain health in numerous ways:(1) Structural
bacterial components such as lipopolysaccharides provide low-grade tonic stimulation of the …

Obesity, inflammation, and the gut microbiota

AJ Cox, NP West, AW Cripps - The lancet Diabetes & endocrinology, 2015 - thelancet.com
As the prevalence of obesity and associated disease continues to rise and concerns for the
spiralling economic and social costs also escalate, innovative management strategies …

Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as …

JA Krumbeck, HE Rasmussen, RW Hutkins, J Clarke… - Microbiome, 2018 - Springer
Background One way to improve both the ecological performance and functionality of
probiotic bacteria is by combining them with a prebiotic in the form of a synbiotic. However …

The role of gut microbiota in atherosclerosis and hypertension

J Ma, H Li - Frontiers in pharmacology, 2018 - frontiersin.org
In recent years, accumulating evidence has indicated the importance of gut microbiota in
maintaining human health. Gut dysbiosis is associated with the pathogenesis of a number of …

Inflammasomes on the crossroads of innate immune recognition and metabolic control

T Próchnicki, E Latz - Cell metabolism, 2017 - cell.com
Inflammasomes are protein complexes formed upon encounter of microbial or damage-
associated stimuli. The main output of inflammasome assembly is activation of caspase-1, a …

The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases

JM Brown, SL Hazen - Annual review of medicine, 2015 - annualreviews.org
The human gastrointestinal tract is home to trillions of bacteria, which vastly outnumber host
cells in the body. Although generally overlooked in the field of endocrinology, gut microbial …

Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability

K de Punder, L Pruimboom - Frontiers in immunology, 2015 - frontiersin.org
Chronic non-communicable diseases (NCDs) are the leading causes of work absence,
disability, and mortality worldwide. Most of these diseases are associated with low-grade …

[HTML][HTML] Polystyrene microplastic exposure induces insulin resistance in mice via dysbacteriosis and pro-inflammation

D Huang, Y Zhang, J Long, X Yang, L Bao… - Science of The Total …, 2022 - Elsevier
Microplastics (MPs) as emerging contaminants have become a global environmental
problem. However, studies on the effects of MPs on metabolic diseases remain limited …