The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Zingiber officinale Roscoe: A comprehensive review of clinical properties

A Bitari, I Oualdi, R Touzani, M Elachouri… - Materials Today …, 2023 - Elsevier
Zingiber officinale Roscoe, commonly known as ginger, is widely used as a spice or a folk
medicine. Such a plant has been incuriously focused on by publishing extensive papers and …

Polyphenol-Rich Ginger (Zingiber officinale) for Iron Deficiency Anaemia and Other Clinical Entities Associated with Altered Iron Metabolism

SL Ooi, SC Pak, R Campbell, A Manoharan - Molecules, 2022 - mdpi.com
Ginger (Zingiber officinale) is rich in natural polyphenols and may potentially complement
oral iron therapy in treating and preventing iron deficiency anaemia (IDA). This narrative …

Pterostilbene and 6-shogaol exhibit inhibitory effects on sunitinib resistance and motility by suppressing the RLIP76-initiated Ras/ERK and Akt/mTOR pathways in …

IC Chiang, SY Chen, YH Hsu, F Shahidi… - European Journal of …, 2024 - Elsevier
Sunitinib (SUN) is the first-line targeted therapeutic drug for advanced renal cell carcinoma
(RCC). However, SUN resistance is frequently observed to result in tumor metastasis, with a …

Ethnopharmacology of medicinal plants used by the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia

WS Bhagawan, W Ekasari, M Agil - Biodiversitas Journal of Biological …, 2023 - smujo.id
Bhagawan WS, Ekasari W, Agil M. 2023. Ethnopharmacology of medicinal plants used by
the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia …

Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability

KK Mak, Z Shiming, R Sakirolla, MK Balijepalli… - Antioxidants, 2023 - mdpi.com
6-shogaol is a natural and the most potent bioactive vanilloid in dried Zingiber officinale
rhizomes. Many scientific studies have reported the diverse biological activities of 6-shogaol …

[6]-Shogaol attenuates oxaliplatin-induced allodynia through serotonergic receptors and GABA in the spinal cord in mice

S Kim, J Gang, JH Lee, H Yang, C Cheon, SG Ko… - Pharmaceuticals, 2022 - mdpi.com
Although oxaliplatin is a well-known anti-cancer agent used for the treatment of colorectal
cancer, treated patients often experience acute cold and mechanical allodynia as side …

Interactive Nutrient Process (INP) in a Generative AI of a New Drug—6-Shogaol as a Potential Case

V Badmaev - Drug Design, Development and Therapy, 2024 - Taylor & Francis
The dynamically evolving science of pharmacology requires AI technology to advance a
new path for drug development. The author proposes generative AI for future drugs …

Kinetic optimization of angkak–red ginger extraction and its impact on antioxidant activity

F Missy, A Fahrurroji, F Nugraha… - Jurnal Teknosains, 2024 - journal.ugm.ac.id
A mixture of angkak and red ginger is a Chinese herbal concoction with potential as an
antioxidant. This herbal combination can be extracted using the kinetic hot maceration …

Atividade anticancerígena do gengibre

MN Antunes - 2023 - ubibliorum.ubi.pt
O presente relatório encontra-se dividido em dois capítulos: o Capítulo 1 versa sobre a
vertente de Investigação e o Capítulo 2 aborda a experiência profissionalizante em …