The role of extracellular vesicles in cancer

R Kalluri, KM McAndrews - Cell, 2023 - cell.com
Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …

Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives

F Seif, Z Torki, H Zalpoor, M Habibi… - Molecular Therapy …, 2023 - cell.com
The tumor microenvironment (TME) comprises a variety of immune cells, among which T
cells exert a prominent axial role in tumor development or anti-tumor responses in patients …

CRISPR/Cas9 delivery strategies with engineered extracellular vesicles

Y Lu, K Godbout, G Lamothe, JP Tremblay - Molecular Therapy-Nucleic …, 2023 - cell.com
Therapeutic genome editing has the potential to cure diseases by directly correcting genetic
mutations in tissues and cells. Recent progress in the clustered regularly interspaced short …

Harnessing exosomes as a platform for drug delivery in breast cancer: A systematic review for in vivo and in vitro studies

AT Gharavi, S Irian, A Niknejad, K Parang… - Molecular Therapy …, 2024 - cell.com
Breast cancer remains a significant global health concern, emphasizing the critical need for
effective treatment strategies, especially targeted therapies. This systematic review aims to …

Therapeutics of Extracellular Vesicles in Cardiocerebrovascular and Metabolic Diseases

Z Hou, Y Lin, X Yang, J Chen, G Li - Extracellular Vesicles in …, 2023 - Springer
Extracellular vesicles (EVs) are nanoscale membranous vesicles containing DNA, RNA,
lipids, and proteins, which play versatile roles in intercellular communications. EVs are …

Gene Therapy of Extracellular Vesicles in Cardiovascular and Metabolic Diseases

ÁF Kovács - Extracellular Vesicles in Cardiovascular and Metabolic …, 2023 - Springer
The ultimate and most complex form of treating human diseases is embodied by gene
therapy. For an effective gene therapeutic product we need to hack the cellular plasma …